Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare ACITRETIN (ACITRETIN) and Apremilast (Otezla) — clinical data, side effects, and patient experiences.
ACITRETIN · Retinoid
How it works
Other agent
Approved for
Otezla · PDE4 Inhibitor
How it works
Inhibits phosphodiesterase 4 (PDE4), increasing intracellular cAMP levels to modulate inflammatory mediator production.
Approved for
Estimated frequency (%) based on clinical trial data
Based on 17 Reddit discussions
ACITRETIN
9%
positive
11 threads
Apremilast
17%
positive
6 threads
% of discussions mentioning each side effect
11 Reddit threads analysed for ACITRETIN
Overall Sentiment
Mixed
Comparison Threads
8
Avg Post Score
6 upvotes
Most discussed side effects in community
Threads directly comparing ACITRETIN to other medications
**.: INTRODUCTION :.** * You don't need to take any supplements. As CDC says: "*More than 90% of new HPV infections, including those caused by high-risk HPV types, clear or become undetectable within 2 years, and clearance usually occurs in the first 6 months after infection*". * People clear HPV in
Hi all, Looking for some input or shared experiences from others in similar shoes. I’ve had psoriasis and PsA for several years now. Current treatment includes: * Methotrexate (MTX) – has helped, but I wouldn't call it a miracle. hasnt changed skin much, I started taking it right as a PsA flare wa
I, 25m 5'11 176lbs constantly get a sore throat all year round, get the flu at least three times a year every now and then catch a cold and almost always have a stuffy nose. I've been diagnosed with hidradenitis suppurativa (mild case treated with acitretin) and because of depression take brintelli
I see that many people here are prescribed Isotretinoin for HS than Acitretin. But from what I have read (research papers on the drugs), Acitretin seems to work better with a number of people going into remissions for 1-4 years. Have anyone been on Acitretin? I am aware that Acitretin affects infert
> **Background:** Treatment of recalcitrant warts represents a continuing therapeutic challenge. Combination therapies can help improve treatment response, decrease adverse effects, and reduce recurrence. > **Objective:** To compare the efficacy, safety and immunological effects of a combined
* [https://imgur.com/a/9qkp9IW](https://imgur.com/a/9qkp9IW) * 27 * Male * 6'2 * 180 * White * Chronic since age 13; severity drastically increased at age 21 * 80% of entire body. * Previous diagnosis of Psoriasis;More recent diagnosis of Pityriasis Rubra Pilaris. * Acitretin, 50 mg/ day I'd appre
Female, 34, have psoriasis. Take cosentyx, acitretin, iron, and birth control all by rx. Non-rx I take Xyzal. Got off 7 day cruise(family event) Monday morning. Went straight to hotel, to wait for 5am flight Tuesday. About 4pm Monday I was hit hard. Vomiting and diarrhea simultaneously(and wtf Seat
I (18 M, Indian, 180cm, 186 lbs) currently on Acitretin for psoriasis and HS for 8 months got a flare-up out of nowhere 2 days ago where my whole body turned red and started burning/itching starting from my chest and ears and gradually spreading to the whole body. It was unbearable. I have my dermat
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
6 Reddit threads analysed for Apremilast
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
2 upvotes
Most discussed side effects in community
This is a 38-year-old female with multiple medical problems including psoriasis and psoriatic arthritis for which she receives secukinumab, apremilast, and leflunomide. She is admitted to the hospital on November 16 for progressive dyspnea and generalized body pain. She has chronic sinus congestio
What’s going on with me is kind of a question mark so I’m thinking of throwing it out to the internet for some ideas. I know my doctors are doing their best and I feel taken care of but not getting any real answers and they’re really overworked with the pandemic. It’s not instead of, because I am be
I'm 17M Asian 5'11 weigh around 190 lbs. I was diagnosed with plaque psoriasis 2 weeks ago. My arms were already getting better and barely any flare-ups were happening as I was using the meds my doctor prescribed which were oral apremilast/otezla 30mg a day and topical 0.5% bethamethasone ointment,
I am a radiologist. I just received antirabies treatment few hours ago. I wonder if topical clobetasol has any effect on efficacy of rabies treatment. I take apremilast 10 mg for psoriasis O.D. Other than that, im taking Vitamin D shots (60000 IU weekly) Non-alcoholic Non-smoker
* **Age:** 24 * **Sex:** M * **Height/Weight:** 170cm / 75 kg * **Race:** Indian (Honestly, I don't know.) * **Primary Complaint:** Questioning treatment plan for Alopecia Areata * **Duration:** 3 years * **Any existing medical issues:** Hypertension and Ulcerative Colitis * **Current medications an
Italia, uomo, 31 anni, 60 kg, non fumatore. Sportivo, da sempre alimentazione sana. Ciao a tutti. Da inizio 2023 ho costantemente ulcere orali, macchie rosse e piccoli rigonfiamenti in bocca. All’inizio erano numerose e molto dolorose; oggi la situazione è più “leggera” ma persiste: di solito
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
ACITRETIN is a Retinoid, while Apremilast belongs to the PDE4 Inhibitor class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
ACITRETIN carries 4 FDA warnings. Apremilast carries 3 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.