Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare ACITRETIN (ACITRETIN) and METHOTREXATE (METHOTREXATE) — clinical data, side effects, and patient experiences.
ACITRETIN · Retinoid
How it works
Other agent
Approved for
METHOTREXATE, Trexall, Otrexup · DMARD
How it works
12.1 Mechanism of Action Methotrexate inhibits dihydrofolic acid reductase. Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before they can be utilized as carrie...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 26 Reddit discussions
ACITRETIN
9%
positive
11 threads
METHOTREXATE
20%
positive
15 threads
% of discussions mentioning each side effect
11 Reddit threads analysed for ACITRETIN
Overall Sentiment
Mixed
Comparison Threads
8
Avg Post Score
6 upvotes
Most discussed side effects in community
Threads directly comparing ACITRETIN to other medications
**.: INTRODUCTION :.** * You don't need to take any supplements. As CDC says: "*More than 90% of new HPV infections, including those caused by high-risk HPV types, clear or become undetectable within 2 years, and clearance usually occurs in the first 6 months after infection*". * People clear HPV in
Hi all, Looking for some input or shared experiences from others in similar shoes. I’ve had psoriasis and PsA for several years now. Current treatment includes: * Methotrexate (MTX) – has helped, but I wouldn't call it a miracle. hasnt changed skin much, I started taking it right as a PsA flare wa
I, 25m 5'11 176lbs constantly get a sore throat all year round, get the flu at least three times a year every now and then catch a cold and almost always have a stuffy nose. I've been diagnosed with hidradenitis suppurativa (mild case treated with acitretin) and because of depression take brintelli
I see that many people here are prescribed Isotretinoin for HS than Acitretin. But from what I have read (research papers on the drugs), Acitretin seems to work better with a number of people going into remissions for 1-4 years. Have anyone been on Acitretin? I am aware that Acitretin affects infert
> **Background:** Treatment of recalcitrant warts represents a continuing therapeutic challenge. Combination therapies can help improve treatment response, decrease adverse effects, and reduce recurrence. > **Objective:** To compare the efficacy, safety and immunological effects of a combined
* [https://imgur.com/a/9qkp9IW](https://imgur.com/a/9qkp9IW) * 27 * Male * 6'2 * 180 * White * Chronic since age 13; severity drastically increased at age 21 * 80% of entire body. * Previous diagnosis of Psoriasis;More recent diagnosis of Pityriasis Rubra Pilaris. * Acitretin, 50 mg/ day I'd appre
Female, 34, have psoriasis. Take cosentyx, acitretin, iron, and birth control all by rx. Non-rx I take Xyzal. Got off 7 day cruise(family event) Monday morning. Went straight to hotel, to wait for 5am flight Tuesday. About 4pm Monday I was hit hard. Vomiting and diarrhea simultaneously(and wtf Seat
I (18 M, Indian, 180cm, 186 lbs) currently on Acitretin for psoriasis and HS for 8 months got a flare-up out of nowhere 2 days ago where my whole body turned red and started burning/itching starting from my chest and ears and gradually spreading to the whole body. It was unbearable. I have my dermat
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for METHOTREXATE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
125 upvotes
Most discussed side effects in community
Edit #3: I passed out today on my apartment steps out of absolutely the worst pain I’ve ever had in my life and someone saw me and called an ambulance. I finally got a diagnosis in the emergency room after bawling my eyes out of frustration at this entire situation and they found out I have a corona
This is going to be so, so, so long and I’m so sorry. But we don’t know what else to do. I’ve tried to compress it the best I could. 3f with medical mystery. First year of life: -couldn’t latch until 2 months old -refused all food, in all forms. -up every 20 minutes every single night, wouldn’t
Hey /r/pharmacy I'm a mod over on the /r/lupus sub and we got our [first report](https://www.reddit.com/r/lupus/comments/vt9owi/denied_my_methotrexate/) from a from an established user of the sub saying their methotrexate prescription has been denied due to the recent overturning of roe. This has [b
I've been dancing my heart out for the last couple days. In public. I don't know why I'm just happy to be alive and moving and I don't even need music. It is honestly so abnormal for me to be dancing that I figured I should ask here? Nothing bad comes from the urge to dance in public yeah? F19 5'4 1
https://www.oscn.net/dockets/GetCaseInformation.aspx?db=oklahoma&number=CF-2023-2233&cmid=4194257 Maybe fuzzy on details, but basically this case was a doc who ordered mtx for a patient and sent the order as qd vs qw. Pharmacist filled it. Patient died. Obviously very sad, we just normally
F23 just ran a 10k. For reference I use to be a big runner so I have pride but haven't ran in a few months so no foundation. Absolutely killed myself to PR today. The race was brutal with cramping in my legs and lower back. I have probably ran hundreds of races. NEVER before have I gotten so immedi
25F USA 130 lbs 5'6 Meds: Prednisone, Cymbalta, 5mg Percocet 3x a day I will appreciate any insight. I'm so frustrated and exhausted I can hardly think straight by this point. Typing this from a hospital bed, actually! I will try to provide how this affects me both physically and mentally, and my st
Be careful and vigilant when dealing with maverick prescribers. Look at this example, the dosage was flagged and followed up on yet dispensed regardless. https://www.theage.com.au/national/victoria/drug-for-common-skin-disorder-implicated-in-grandfather-s-death-20180206-p4yzik.html
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
ACITRETIN is a Retinoid, while METHOTREXATE belongs to the DMARD class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
ACITRETIN carries 4 FDA warnings. METHOTREXATE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.