ADALIMUMAB vs GUSELKUMAB

I am writing this because I am still in shock and honestly struggling to process what happened. I want to know if anyone else with Crohn’s or IBD has experienced something like this and how you dealt with it. I am a 23 year old woman with a severe course of Crohn’s disease affecting the terminal il

31F, 5'6, 145 lbs, white, occasional smoker Humira (adalimumab - for hidradentitis suppurativa) Lamotrigine (mood) Buspirone (anxiety) Vyvanse (ADHD) Let's start off by saying I'm an idiot - when I started taking Humira for my HS a couple years ago I read every about it. I know I am not supposed t

***Disclaimer: This newsflash is for informational purposes. Always consult with your IBD-specialized dietitian or GI team before making significant dietary changes.*** The therapeutic paradigm for ulcerative colitis has shifted fundamentally between 2024 and 2026, transitioning from a reactive

A Quick catch you up on the Rani pill: They have completed a phase one trial of Octreocide in 2019, they still have Phase 2 phase 3 & FDA Approval before commercialization. and have multiple other drug candidates in the background. Capsule dissolves after being swallowed in the small intestine.

**The Scientific History of Adalimumab** Adalimumab is a powerful anti-inflammatory that acts against cytokines, which are protein messengers between cells, that would otherwise encourage inflammation to occur. Adalimumab targets a specific cytokine, TNF, and so we call adalimumab an anti-TNF dr

#Earnings Abbott Laboratories (ABT) Q3 EPS USD 0.75 vs. Exp. USD 0.75, revenue USD 7.7bln vs. Exp. USD 7.65bln. Narrows FY EPS guidance (to USD 2.87-2.89 from 2.85-2.91), but says despite FX headwinds, it is positioned to achieve upper end of its guidance. (Newswires) Cree (CREE) Q1 Adj. EPS US

Hey everyone! I've been on a deep dive into understanding the immune system, particularly in relation to psoriasis. Consolidating information like this really helps me grasp it better. While there's a wealth of knowledge out there, I've highlighted both natural and conventional methods that I've per

Hi all, have had worsening psoriasis and PsA since 2014 and finally today my dermatologist saw me and has put me forward for Adalimumab! I am so happy to finally get approved for a biologic. Fingers crossed it will be the treatment that finally works for me!

Started Skyrizi on Sunday and things are changing. As the old adage goes "Changeable, Curable" I've had one small area of persistent psoriasis clear completely - I'd given it a friction burn from rubbing through clothes on Saturday. On Monday it was red and sore. Tuesday it had dried. Wednesday it p

I’m 23M with psoriasis. I’ve used methotrexate before, then Apremilast for 6 months (stopped working). Now my doctor wants to put me on Tofacitinib, but also asked me to check with insurance about biologics. Shes recommending Ixekizumab (Taltz), but it’s super expensive (₹3–4.5 lakh first year, then

If you'd all humour me while I vent, I'm very much an emotional wreck atm 😅 I've had Plaque Psoriasis since 2012, started on my forehead and then spread to cover my entire face, big patches on my legs, arms, back torso, scalp, ears... You get the drift. After Ciclosporine in 2019 I took a break wit

It's not every day you find a promising pennystock before it pops, and if you've been looking for one then you're gonna want to read this. I've been wanting to write a definitive DD post for this stock for a while but haven't had the time until now. There's been a few good posts about it but none ha

Hi everyone, first, just want to thank everyone for sharing in this forum, for the courage to reveal and be vulnerable, for providing a sense of community and connection when its easy to feel alone in what we're struggling with, and for the encouragement and support. About me: 51yo male with recen

I use the biologic in the photo. My doctor gave me the first injection, and today I have to do the second injection by myself. I wanted to ask if you inject yourself? Is it easy? I

My gf has been prescribed to get Secukinumab (Scapho) for 5 weeks, then monthly after, and Guselkumab (Tremfya) once a month (afaik this is conditional to her response to Scapho in the first 4 weeks). She's being charged 32k for Secukinumab and 82k for Guselkumab per session. Are there any availabl

So..we don't exactly know for sure even whether the injection had a direct effect or was merely acting on the gut microbiome which then quenched the inflammation. # Compositional Alteration of Gut Microbiota in Psoriasis Treated with IL-23 and IL-17 Inhibitors [Yu-Huei Huang](https://pubmed.ncbi.nl

Hi All, I was able to join a clinical trial for Guselkumab and had my first dose 3-4 weeks ago. Just wondering if any of you had experienced an onset of Migraine as a side effect of the medicine? Also, maybe more acne? Thanks!

***EDIT: I am in the US. I have my next GI follow up to likely begin Tremfya on 10/7. I did my labs today for calprotectin, TB, HIV, CBC, CMP, Hepatitis, and TPMT activity. Hi everyone, I stopped into my GI today and got copies of my colonoscopy, biopsy, and follow-up visit note with my GI from las

I was diagnosed with Psoriasis last March 2024. 3 months later, I started Guselkumab (Tremfya). Since then, my skin really cleared up. No flares. I feel normal and back with my old self except that I have hyperpigmentation on some areas but not really a big problem. Been taking this biologic for 8 m