AMIKACIN vs GENTAMICIN

Last week there were a few headlines related to “the superbug doctors have been dreading,” and some comments regarding sensationalism. I wanted to take a couple paragraphs to review the facts and discuss the clinical implications, while hopefully avoiding sensationalism. **Where it all Began** The s

Age: 63 Sex: male Height: 6,1 (185 cm) Weight: approx 187, was 220 before it all started (85 kg, used to be 100 kg) Race: Caucasian Duration of complaint: 8 weeks Location: Italy - body: systemic condition Existing medical issues: hypertension, lung cancer in the right lung treated in 2018 (adenocar

We don't do it already at my site, but I want to propose to my directors that we institute a Pharmacist driven drug monitoring program. I know it's done to some capacity at some hospitals, but I can't seem to find any literature on it or policies online. Only that the AMA was against it in 2000 (to

I (38M) suffered from perforated appendicitis a month ago and had to have open abdomen surgery, and after the surgery a drain was setup. 4 days after the operation the drain started draining thick pus, and I was kept in hospital for another 16 days. While I was in hospital for the 20 days in total,

Mikolaj 5 years, old, male, Diagosed atypical ASD, Poland I am a desperate father from Poland turning into an investigator. My son was born with severe complications (now diagnosed with Cerebral Palsy/MPD). The hospital claims it was due to "maternal diabetes" and "intrauterine infection." Lawyers h

So tonight I had this pt with a recent history of AGEP (Acute generalized exanthematous pustulosis) basically a rare drug induced severe skin reaction similar to TENS/SJS/DRESS. They also have AKI on questionable CKD presumably caused by inflammation that is resolving slowly. Nephrology recommends a

Hey team. Has anyone got any experience or references with 3x weekly IV amikacin therapeutic drug monitoring? Have a patient at the moment who is developing high requencey hearing loss. Any help is welcome. Thanks!

I work at a hospital. First time it was close to midnight, I ordered a vanc to start the next morning. I chose for the regime to "start tomorrow", then verified it after midnight so that it started the following day. The person went over 24 hours without vanc. Yesterday, the same thing happened wit

Pharmacists, technicians, and all you other people suffering with us - where do you turn to when you receive an off-the-wall drug request or question? And, if you work in hospital or some other location where you deal with bladder irrigations, how do you compound yours? Do you use bottles of NS? Do

Hey guys, I’m servicing a new hospital that serves pediatric patients and newborns. I see a lot of amp/gent for newborns with suspected EOS, critical drips on pediatric patients, vancomycin, opioids, even epidurals. I’m all so new to this patient population and I’ve been trying so hard to look up

What's everyone doing at their hospital with regards to antibiotic lock therapy (ALT)? I currently work at a medium sized community teaching hospital without much in the way of policies. Our line infections are getting out of hand, especially in regards to our IHD population using tunneled catheters

I'm trying to find more information about extended interval aminoglycoside dosing, specifically gentamicin at 5 mg/kg. There doesn't seem to be much data out there, but there are a few different nomograms available including Urban and Craig, Ritchie, etc. Is there any nomogram that is specifically

Feel free to delete if this isn’t allowed, but I could use some insight on how to approach this problem. \*\*Edited for clarity and fixing mistakes I realize now that I mistakingly put vancomycin instead of phenytoin in this title of this—so for that I apologize because it changes everything about h