Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare BREXPIPRAZOLE (Rexulti) and BUPROPION (bupropion) — clinical data, side effects, and patient experiences.
Rexulti · Atypical Antipsychotic
How it works
Atypical Antipsychotic agent
Approved for
bupropion, Wellbutrin, Zyban · Atypical Antidepressant (NDRI)
How it works
12.1 Mechanism of Action The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradre...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 25 Reddit discussions
BREXPIPRAZOLE
25%
positive
12 threads
BUPROPION
54%
positive
13 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for BREXPIPRAZOLE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
8 upvotes
Most discussed side effects in community
I just want to ask given that I am in the middle of the wasteland that is the Neuroscience Pipeline, what keeps you guys in your field? In the past 24 months we have seen go down in flames: Alzheimer's Bapineuzumab, Semagacestat, Avagacestat, Lilly's BACE-1 inhibitor, Solanezumab, Gammagard (IVIG
Longer explanation below. Before i start- I AM going to call my Dr. tomorrow. I just need some advice because it's hard for me to advocate for myself. 28 yo. female, 5'7" and 200lbs, Caucasian Diagnosed with Bipolar II, OCD, and GAD Current medications: **Luvox** (fluvoxamine) CURRENTLY:
I previously had written a long file with all my story with a lot of information, some of which even incorrect, so I’ll try to be as short as possible in this one, since now I know the DIRECT physical cause, even if I still don’t know what in my body is ill/malfunctioning: I’m 20 years old, male,
I am a 23 year old male and I need help. I don’t know how to quite put it into words but I am just always extremely exhausted. But it’s not just a feeling of tiredness or fatigue like if you stayed up too late or even for days on end. It is full body and completely overwhelming. It feels like every
i couldn't find the complete chemical classification of antipsychotics on the internet. can someone tell me if this is correct? typical / 1st gen 1. phenothiazines a. aliphatic side chain - chlorpromazine, triflupromazine b. piperidine side chain - thioridazine c. piperazine side chain - trifluopera
36M, autism, had a fundoplication for a hiatal hernia when in my late teens. Have had basically no interest in food for several months. Not hungry, and no appetite. Labs seemed fine last I looked, but will have them drawn again soon. .5 mg brexpiprazole 200 mg pregabalin bid too much cannab
Age/Sex: 24F Height/Weight: 5’1”, 120 lbs Duration of Symptoms: Since childhood (worsening in adulthood, especially past 1–2 years) Location of Symptoms: Widespread — joints, skin, cardiovascular, GI, urologic, neurological, endocrine ⸻ 🧠 Summary of Concern I’m a 24-year-old female with a lifelong
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
13 Reddit threads analysed for BUPROPION
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
69 upvotes
Most discussed side effects in community
As I get older, I’m starting to become more aware of the telltale signs that my depression symptoms are getting worse. I’ve noticed that one very specific symptom is that I feel nostalgic about so many things. In a melancholy way, not a fun way. I think it’s my brain’s way of trying to comfort me by
I obviously am not cured but it’s easily my favorite one I’ve been on. I want to know if y’all have ever started a med and were just blown away!! For me, it’s Bupropion (Wellbutrin XL). It helped reduce my depression smoking and my lack of motivation. I’ve genuinely never been happier. ETA: It’s bee
I have been a reader of this sub-reddit for some time now, but it is time for me to post. I am a first generation Asian-American and I have severe depression. I am taking bupropion sr1 at 50mg. The meds work for the most part to the extent that I can function, but at times I feel a huge surge of
So as the title suggests, ive recently come out of a huge stent of depression, about 10 years worth. Because of how long ive been depressed, most of my entire personality was taken over by it. I became withddrawn, self defeating, gave up my activities and hobbies years ago because they were no long
I have been so exhausted lately that I am on the verge of dizziness some days. I get about eight hours of sleep, so I should be well rested enough, but I wake up barely able to get out of bed. It's also really cold right now, which is sapping a lot of what little energy I have left. I am trying not
After four years on a low dose of bupropion XL (100 mg) , I decided to stop taking it. My pharmacist told me to taper off slowly, so for the first 2.5 weeks I took it every 2nd day, and for the next 2.5 weeks I took it every 3rd day. The tapering process went smoothly, so I figured it was safe to st
I’ve been depressed and anxious since I was 10 (turning 22 this year..) and it almost feels like every year, I just lose a piece of myself. Every year, I lose more energy and more hope. I struggle with so much self doubt and self hatred. I wouldn’t kill myself but I often think of how great it would
I'm only 4 foot 10, and gained about 15 pounds in 4 months on mirtazapine. That is something like the equivalent of 6 or 8 dress sizes. I need to stay on the drug because of the severity of my depression and sleep dysfunction, with long covid. Over the course of 2 months I've lost 9 of those pounds,
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
BREXPIPRAZOLE is a Atypical Antipsychotic, while BUPROPION belongs to the Atypical Antidepressant (NDRI) class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
BREXPIPRAZOLE carries 4 FDA warnings. BUPROPION carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.