Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare BREXPIPRAZOLE (Rexulti) and DULOXETINE (DULOXETINE HYDROCHLORIDE) — clinical data, side effects, and patient experiences.
Rexulti · Atypical Antipsychotic
How it works
Atypical Antipsychotic agent
Approved for
DULOXETINE HYDROCHLORIDE, Cymbalta · SNRI
How it works
12.1 Mechanism of Action Although the exact mechanisms of the antidepressant, central pain inhibitory and anxiolytic actions of duloxetine in humans are unknown, these actions are ...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 27 Reddit discussions
BREXPIPRAZOLE
25%
positive
12 threads
DULOXETINE
27%
positive
15 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for BREXPIPRAZOLE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
8 upvotes
Most discussed side effects in community
I just want to ask given that I am in the middle of the wasteland that is the Neuroscience Pipeline, what keeps you guys in your field? In the past 24 months we have seen go down in flames: Alzheimer's Bapineuzumab, Semagacestat, Avagacestat, Lilly's BACE-1 inhibitor, Solanezumab, Gammagard (IVIG
Longer explanation below. Before i start- I AM going to call my Dr. tomorrow. I just need some advice because it's hard for me to advocate for myself. 28 yo. female, 5'7" and 200lbs, Caucasian Diagnosed with Bipolar II, OCD, and GAD Current medications: **Luvox** (fluvoxamine) CURRENTLY:
I previously had written a long file with all my story with a lot of information, some of which even incorrect, so I’ll try to be as short as possible in this one, since now I know the DIRECT physical cause, even if I still don’t know what in my body is ill/malfunctioning: I’m 20 years old, male,
I am a 23 year old male and I need help. I don’t know how to quite put it into words but I am just always extremely exhausted. But it’s not just a feeling of tiredness or fatigue like if you stayed up too late or even for days on end. It is full body and completely overwhelming. It feels like every
i couldn't find the complete chemical classification of antipsychotics on the internet. can someone tell me if this is correct? typical / 1st gen 1. phenothiazines a. aliphatic side chain - chlorpromazine, triflupromazine b. piperidine side chain - thioridazine c. piperazine side chain - trifluopera
36M, autism, had a fundoplication for a hiatal hernia when in my late teens. Have had basically no interest in food for several months. Not hungry, and no appetite. Labs seemed fine last I looked, but will have them drawn again soon. .5 mg brexpiprazole 200 mg pregabalin bid too much cannab
Age/Sex: 24F Height/Weight: 5’1”, 120 lbs Duration of Symptoms: Since childhood (worsening in adulthood, especially past 1–2 years) Location of Symptoms: Widespread — joints, skin, cardiovascular, GI, urologic, neurological, endocrine ⸻ 🧠 Summary of Concern I’m a 24-year-old female with a lifelong
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for DULOXETINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
43 upvotes
Most discussed side effects in community
I am a 28 year old man and I've just realized that nothing interests me. I believe that it might be connected to depression as I am on medication for depression and anxiety (duloxetine) I am not really sad or anything. I am just very neutral. Things that used to interest, excite me and make me happ
I have been recovering from over a decade of major depressive disorder and recently diagnosed bipolar II. I’m seeing light at the end of the tunnel with Lamotrigine and lifestyle changes, and after several mental health evaluations, my psychiatrist gave me the best news ever; I can stop taking antid
Hi, just wondering if this is a common experience: So i've been taking agomelatine 50mg for about 5 months and duloxetine 60mg for 3 months now for severe depression and anxiety. The antidepressants have been working just as intended in the sense that most of the mental agony has gone, but there's
I ( M23) have been taking duloxetine 60 mg for 2 years now. While it has helped tremendously with my anxiety/depression/DPDR, it did cause sexual side effects for me. (I also take lamotrigine, but that is unlikely to cause effects like this) For me, these sides were very annoying; my main problem wa
Entry time 8:55am Before I went to sleep last night, I had nurses come 2 times, around 9:30pm and then at 10:40pm asking if I wanted to take some anxiety medication to help me sleep better. I refused both times as it wasn't initially prescribed, and in general I don't have a problem sleeping. My al
UHC is canceling coverage of my medication: Lamotrigine, Atomoxetine, and Duloxetine. Starts in January. Im barely getting by as it is. I need to find new insurance asap (Im in the USA). Its no wonder they were targeted. I just learned that they deny the most coverage of any US health insurer. Wtf a
Since the late of 2019 year, till now I've tried: 1- Escitalopram "Lexapro" (tried Atomoxetine "Strattera" with it, then stopped it due to its bad effects) (tried Risperidone "Rispardal" then stopped it, it hasn't only bad effects, but also highly increased prolactin) 2- Fluoxetine "Prozac" 3- Bupro
You know how a lot of sources say working towards a goal and then achieving it gives a sense of reward via dopamine? This week I got a pay rise, achieved a fitness goal I've been working towards for months and even got asked out on a date by someone quite attractive. But I feel absolutely nothing.
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
BREXPIPRAZOLE is a Atypical Antipsychotic, while DULOXETINE belongs to the SNRI class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
BREXPIPRAZOLE carries 4 FDA warnings. DULOXETINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.