Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare BUPROPION (bupropion) and ORLISTAT (Xenical) — clinical data, side effects, and patient experiences.
bupropion, Wellbutrin, Zyban · Atypical Antidepressant (NDRI)
How it works
12.1 Mechanism of Action The mechanism of action of bupropion is unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradre...
Approved for
Xenical · Weight Management
How it works
12.1 Mechanism of Action Orlistat is a reversible inhibitor of gastrointestinal lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by formi...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 20 Reddit discussions
BUPROPION
54%
positive
13 threads
ORLISTAT
29%
positive
7 threads
% of discussions mentioning each side effect
13 Reddit threads analysed for BUPROPION
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
69 upvotes
Most discussed side effects in community
As I get older, I’m starting to become more aware of the telltale signs that my depression symptoms are getting worse. I’ve noticed that one very specific symptom is that I feel nostalgic about so many things. In a melancholy way, not a fun way. I think it’s my brain’s way of trying to comfort me by
I obviously am not cured but it’s easily my favorite one I’ve been on. I want to know if y’all have ever started a med and were just blown away!! For me, it’s Bupropion (Wellbutrin XL). It helped reduce my depression smoking and my lack of motivation. I’ve genuinely never been happier. ETA: It’s bee
I have been a reader of this sub-reddit for some time now, but it is time for me to post. I am a first generation Asian-American and I have severe depression. I am taking bupropion sr1 at 50mg. The meds work for the most part to the extent that I can function, but at times I feel a huge surge of
So as the title suggests, ive recently come out of a huge stent of depression, about 10 years worth. Because of how long ive been depressed, most of my entire personality was taken over by it. I became withddrawn, self defeating, gave up my activities and hobbies years ago because they were no long
I have been so exhausted lately that I am on the verge of dizziness some days. I get about eight hours of sleep, so I should be well rested enough, but I wake up barely able to get out of bed. It's also really cold right now, which is sapping a lot of what little energy I have left. I am trying not
After four years on a low dose of bupropion XL (100 mg) , I decided to stop taking it. My pharmacist told me to taper off slowly, so for the first 2.5 weeks I took it every 2nd day, and for the next 2.5 weeks I took it every 3rd day. The tapering process went smoothly, so I figured it was safe to st
I’ve been depressed and anxious since I was 10 (turning 22 this year..) and it almost feels like every year, I just lose a piece of myself. Every year, I lose more energy and more hope. I struggle with so much self doubt and self hatred. I wouldn’t kill myself but I often think of how great it would
I'm only 4 foot 10, and gained about 15 pounds in 4 months on mirtazapine. That is something like the equivalent of 6 or 8 dress sizes. I need to stay on the drug because of the severity of my depression and sleep dysfunction, with long covid. Over the course of 2 months I've lost 9 of those pounds,
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
7 Reddit threads analysed for ORLISTAT
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
267 upvotes
Most discussed side effects in community
I'm 20F, 5' 9" (175cm). SW255, CW140, GW140. So a couple of years ago my doctor suggested that I do a low-fat diet with 6-7 small 250cal meals per day, basing them on whole grains and some very lean protein with a fruit, and taking orlistat with meals that had more fat than usual. I tried that and f
I wanted to share my experience in case it helps anyone fighting with their insurance or pharmacy benefit manager (PBM) to get coverage for **Mounjaro or Zepbound**. I’m a **Massachusetts resident (47F, 5’6”) with a BMI of 37.1 in 9/2022**. I have **hypertension and moderate sleep apnea (AHI=15)**,
This sub has been a huge source of info. and comfort to me and I wanted to share my story in case it may help those considering Sema for weight loss: I started on Sema for "vanity" reasons. I have struggled with a borderline ED and body dysmorphia all my life, having grown up a as a dancer without
I read so much negative stuff about orlistat on this forum and elsewhere, and thought I should take time to share my experience. A lot people describe an uneasy feeling in their stomach when eating fat on orlistat. I do have *a *feeling too, but I don't think it's uncomfortable. I just feel... satia
Greetings, Long time lurker, v. rare poster. Came here because I was prescribed Orlistat, got the dreaded oily diarrhea, scoured the internet for answers to no avail and eventually found a solution myself. I reckon reddit is the best possible place to put this info for any other poor souls scourin
Hi everyone. I am mainly writing this for cathartic reasons. I have struggled with weight my entire life and I never feel like talking to my friends or tweeting about it quite captures my life. I welcome any comments, criticisms, or words of support. ​ TLDR: I'm a smart guy and have had s
Another struggling to lose weight with pcos post! I exercise regularly - bike to the gym in the morning, yoga or dance in my lunch break and some kind of activity at night like swimming or walking. My eating habits are pretty good - healthy home prepared meals. I try to be mindful of carbs and sug
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
BUPROPION is a Atypical Antidepressant (NDRI), while ORLISTAT belongs to the Weight Management class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
BUPROPION carries 4 FDA warnings. ORLISTAT carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.