CYCLOSPORINE vs GUSELKUMAB

Is IV cyclosporine 3 mg/kg, for example, the same as PO cyclosporine 3 mg/kg? It seems like many providers treat it this way, 1:1 conversion but some sources online say 3:1? Could you help explain the difference in practice vs. online sources? Thank you!

Our department hired a new NP recently and is shadowing in clinic. She was asking about cyclosporine and I made an off the cuff remark that she shouldn't be too worried because she shouldn't be prescribing it anyway (after educating her about the labs to follow, doses etc.). When she leaves she says

Yesterday I was at work, sitting at my desk looking at my computer screen. I started to notice black splotches appearing in my vision, similar to what I have seen in the past when I have stood up too fast. I have never experienced this sitting down before but I wasn't alarmed and figured I'd wait it

this is about my aunt (female, late 50s, black, high BMI) just now. her reading came down to 195/97 on the arm cuff machine we have at home but im really worried. she’s already on BP meds (and a plethora of other meds). she started a regimen of cyclosporine for membranous nephropathy(sp?) and protei

I apologize for the strained wording. I tried to Google this but I couldn't figure out the right search terms. In the US, generally health insurance will not pay for medications prescribed for non-FDA-approved/"off-label" uses, and/or for compounded medications. It is completely legal to prescribe o

Age: 64 Sex: F Primary medical issue: Mother was diagnosed with AML FLT3 TKD in September of 2021 * Current medication: Mag, Calcium+Vit D, Acyclovir * Current Care: Every other week visit with either local oncologist or nurse practitioner, every couple months telemedicine with Fred Hutch clinic

* **Age**: 26 * **Sex**: Male * **Height**: 6'2" * **Weight**: \~145lbs * **Race**: Caucasian * **Duration of complaint:** 2 years for red cell aplasia, 8 years for CVID * **Location** (Geographic and on body):Denver, CO * **Any existing relevant medical issues (if any):** Red Cell Aplasia, CVID, Hx

Hello all, I'm looking for advice/insight into my medical history. I'm a 38 year-old man, diagnosed with Autoimmune Hemolytic in Jan 2018. Since then I've relapsed twice, with the least severe episode being the last in OCT 2020. The first and last episodes were treated with oral corticosteroids, an

This is too much isn't it? I need advice!  I'm unsure which of my doctors can help me and hoping someone here can tell me which doctor to talk to, what questions to ask, and what I might be overlooking or misinterpreting. I live in East Texas. My husband has great health insurance, but we have v

It's not every day you find a promising pennystock before it pops, and if you've been looking for one then you're gonna want to read this. I've been wanting to write a definitive DD post for this stock for a while but haven't had the time until now. There's been a few good posts about it but none ha

Hi everyone, first, just want to thank everyone for sharing in this forum, for the courage to reveal and be vulnerable, for providing a sense of community and connection when its easy to feel alone in what we're struggling with, and for the encouragement and support. About me: 51yo male with recen

I use the biologic in the photo. My doctor gave me the first injection, and today I have to do the second injection by myself. I wanted to ask if you inject yourself? Is it easy? I

My gf has been prescribed to get Secukinumab (Scapho) for 5 weeks, then monthly after, and Guselkumab (Tremfya) once a month (afaik this is conditional to her response to Scapho in the first 4 weeks). She's being charged 32k for Secukinumab and 82k for Guselkumab per session. Are there any availabl

So..we don't exactly know for sure even whether the injection had a direct effect or was merely acting on the gut microbiome which then quenched the inflammation. # Compositional Alteration of Gut Microbiota in Psoriasis Treated with IL-23 and IL-17 Inhibitors [Yu-Huei Huang](https://pubmed.ncbi.nl

Hi All, I was able to join a clinical trial for Guselkumab and had my first dose 3-4 weeks ago. Just wondering if any of you had experienced an onset of Migraine as a side effect of the medicine? Also, maybe more acne? Thanks!

***EDIT: I am in the US. I have my next GI follow up to likely begin Tremfya on 10/7. I did my labs today for calprotectin, TB, HIV, CBC, CMP, Hepatitis, and TPMT activity. Hi everyone, I stopped into my GI today and got copies of my colonoscopy, biopsy, and follow-up visit note with my GI from las

I was diagnosed with Psoriasis last March 2024. 3 months later, I started Guselkumab (Tremfya). Since then, my skin really cleared up. No flares. I feel normal and back with my old self except that I have hyperpigmentation on some areas but not really a big problem. Been taking this biologic for 8 m