CYCLOSPORINE vs UPADACITINIB

Is IV cyclosporine 3 mg/kg, for example, the same as PO cyclosporine 3 mg/kg? It seems like many providers treat it this way, 1:1 conversion but some sources online say 3:1? Could you help explain the difference in practice vs. online sources? Thank you!

Our department hired a new NP recently and is shadowing in clinic. She was asking about cyclosporine and I made an off the cuff remark that she shouldn't be too worried because she shouldn't be prescribing it anyway (after educating her about the labs to follow, doses etc.). When she leaves she says

Yesterday I was at work, sitting at my desk looking at my computer screen. I started to notice black splotches appearing in my vision, similar to what I have seen in the past when I have stood up too fast. I have never experienced this sitting down before but I wasn't alarmed and figured I'd wait it

this is about my aunt (female, late 50s, black, high BMI) just now. her reading came down to 195/97 on the arm cuff machine we have at home but im really worried. she’s already on BP meds (and a plethora of other meds). she started a regimen of cyclosporine for membranous nephropathy(sp?) and protei

I apologize for the strained wording. I tried to Google this but I couldn't figure out the right search terms. In the US, generally health insurance will not pay for medications prescribed for non-FDA-approved/"off-label" uses, and/or for compounded medications. It is completely legal to prescribe o

Age: 64 Sex: F Primary medical issue: Mother was diagnosed with AML FLT3 TKD in September of 2021 * Current medication: Mag, Calcium+Vit D, Acyclovir * Current Care: Every other week visit with either local oncologist or nurse practitioner, every couple months telemedicine with Fred Hutch clinic

* **Age**: 26 * **Sex**: Male * **Height**: 6'2" * **Weight**: \~145lbs * **Race**: Caucasian * **Duration of complaint:** 2 years for red cell aplasia, 8 years for CVID * **Location** (Geographic and on body):Denver, CO * **Any existing relevant medical issues (if any):** Red Cell Aplasia, CVID, Hx

Hello all, I'm looking for advice/insight into my medical history. I'm a 38 year-old man, diagnosed with Autoimmune Hemolytic in Jan 2018. Since then I've relapsed twice, with the least severe episode being the last in OCT 2020. The first and last episodes were treated with oral corticosteroids, an

This is too much isn't it? I need advice!  I'm unsure which of my doctors can help me and hoping someone here can tell me which doctor to talk to, what questions to ask, and what I might be overlooking or misinterpreting. I live in East Texas. My husband has great health insurance, but we have v

For context: for pretty much all of last year over 80% of my body was covered in eczema rash. It was so severe I couldn't use the shower and had to either take baths or wash myself in the sink. My scalp was constantly peeling and I was *always* itchy. While my skin would get better in summer, it was

#Earnings Advance Auto Parts (AAP) Q4 Adj. EPS USD 1.17 vs. Exp. USD 1.13, revenue USD 2.1bln vs. Exp. USD 2.11bln, SSS increased by 3.4%. Sees FY19 revenue USD 9.65bln-9.8bln vs. Exp. USD 9.78bln. (Newswires) Continental Resources (CLR) Q4 Adj. EPS USD 0.54 vs. Exp. USD 0.62, revenue USD 1.15

Hey everyone! I just wanted to provide some sort of update having been on Upadacitinib for just over a month. My eczema is gone and I no longer need to take cold showers and I don't even need to moisturise after showers. My skin looks healthy and clear it is so surreal. This medication is not a ste

Welcome back to this week's newsflash 1. Vedolizumab, a medication used for ulcerative colitis, shows promise in treating chronic pouchitis as well. A new study found it to be effective in reducing ulcer count and inducing mucosal healing. Do you want to know [more](https://www.healio.com/news/gastr

I am interested in participating in a clinical trial. I am leaning towards the 3 mentioned in the title, though I would love to hear about any others that seem promising. I am hoping there will be phase 3 trials in my area some time in the first half of 2018 for ABT-494 and PF-04965842. Phase 3 for

About 80% of my body was covered when I went to the dermatologist, so he sent me to hospital for inpatient treatment for 5 days. I did a paraffin bath -> topical steroid -> wet wrap -> emollient treatment twice a day and everything has cleared up. I've been given a metric tonne of moisturiz

Almost a year ago, after years of worsening Atopic Dermatitis, i said enough is enough, and decided to buy Upadacitinib, a JAK inhibitor originally used for rheumatoid arthritis, after reading about very promising clinical trials for AD. When i posted about it many of you guys were surprised about

Hi there, I wanted to share my experience with eczema and how, in the past 1.5 years, these drugs changed my life: **Growing up and coping:** I’ve had eczema since I was six years old. It started on my elbows, ankles, and on my thigh where I had operations as a child. Around 10 or 11, it spread. I t