Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare DESVENLAFAXINE (Desvenlafaxine) and FLUOXETINE (Fluoxetine) — clinical data, side effects, and patient experiences.
Desvenlafaxine, Pristiq · SNRI
How it works
12.1 Mechanism of Action The exact mechanism of the antidepressant action of desvenlafaxine is unknown, but is thought to be related to the potentiation of serotonin and norepineph...
Approved for
Fluoxetine, Prozac · SSRI
How it works
12.1 Mechanism of Action Although the exact mechanism of fluoxetine is unknown, it is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin.
Approved for
Estimated frequency (%) based on clinical trial data
Based on 27 Reddit discussions
DESVENLAFAXINE
21%
positive
14 threads
FLUOXETINE
38%
positive
13 threads
% of discussions mentioning each side effect
14 Reddit threads analysed for DESVENLAFAXINE
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
143 upvotes
Most discussed side effects in community
Threads directly comparing DESVENLAFAXINE to other medications
I’ve been doing some reading about the 2 available forms of desvenlafaxine, but I think I’ve confused myself at this point. Other than the salt form, is there any major difference between the two? When looking at FDA orange book online, Desvenlafaxine ER succinate has an AB rating to Desvenlafaxine
I have been dealing with mysterious tachycardia and heart palpitations for almost a decade. I have no genetic or lifestyle flags for heart issues, and basically have just been told I should try more cardio and cut out the caffeine. For reference, my usual resting heart rate hangs around 95-105bpm. T
EDIT: Thank you so much to everyone who replied to this post I really appreciate all the inputs, you guys are seriously more helpful then some doctors I have seen. I've got a lot more to think about in terms of what my issues could be caused by including POTS which I think is a real possibility, ADH
I'm a [20M] 6'3 238 lbs I dont smoke tobacco, I do smoke pot, I'm on desvenlafaxine and. Amitriptyline. and an hour ago I accidentally inhaled my water bottle cap, it went down my throat easily and now an hour and a half later I'm gassy and bloated and feel overall icky, should I go to the ER? Shou
I cannot find anything about mechanism pointing towards the uniqueness of duloxetine over venlafaxine or desvenlafaxine.
Subject of post (my gf- she is too anxious about this to post for herself) is 38 female, 5'2, 240lbs approx, takes methimazol, famotidine, adderall, desvenlafaxine, vit d. Just got off seroquel that she had been on for years. She suffers from MS, adhd, major depression, asthma, bipolar 1, and season
About a month ago I (19F) was prescribed Buspirone for anxiety and Desvenlafaxine for depression. These medications were chosen after I took a Genesight test and the results showed them to be among the best options. The person that prescribed them was not my usual consultant, but was the person I wa
I am a pharmacy technician with over 20 years of experience across just about every faction of pharmacy besides Big Pharma/R&D. I currently have a full time job in RX finance, and an evening gig in LTC data entry. The other day at my part time shop, I literally happened upon a script by chance
I (29F) learned in another Reddit thread that Miralax is derived from polyethylene glycol, a petroleum-based compound, derived from petroleum byproducts. This information obviously freaks me out. All of my medications have constipation/hard bowel movements as a side effect (Desvenlafaxine, clonidin
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
13 Reddit threads analysed for FLUOXETINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
185 upvotes
Most discussed side effects in community
I am depression. The person I used to be is gone, there is no going back from this. I'm just sat In the hospital while my mum speaks to cahms, trying to hide my neck from all the other patients. I'm desperate to leave the hospital and get home but I know I'm gonna try again eventually. I've been on
Started seeing a therapist in April 2013 because my mum was worried about me. The therapist was in her mid 20's, and was pretty, so I felt a level of attraction to her, and told her a lot of things about me that I hadn't told anyone. I was in high school at the time, an all boys one, so she was basi
Hello everyone, my name is Samuel, I'm 14 years old and I'm Brazilian. I've been having these thoughts for about two or three years, but in the last few days they've gotten a lot worse. especially after I started taking fluoxetine I think about suicide all day and it haunts me all the time, I can'
I feel like the anti-anxiety effects of this drug (Fluoxetine AKA Prozax), which have been good in a lot of ways, have caused me to lose a certain sense of 'urgency' or 'appropriate' anxiety towards things like academic deadlines etc. Things I really should be worrying about don't really make me anx
Hi! hope someone who is not feeling good read this. I tried to commit suicide two years ago. in fact, using another reddit account I found help with this community before, and people was really nice!.. So now I want to write this just to i dunno... maybe put some hope in at least someone. I've bee
A brief summary: so I had major depression & severe for anxiety for about 1.5yrs, it was serious & I was at an all time low, hospital admissions, the lot. Doctors suspected it was drug induced (from MDMA), which I completely agree with, it was the time I spiralled down HARD, and also situati
I am on 20mg of fluoxetine and it’s stopping me from crying almost completely, I can occasionally squeeze out a tear or two and I’ve had one been breakdown when I was drunk but other than that the feelings build in my body and I feel worse and worse but it has nowhere to go. I’m also breaking out in
7 months ago, I took fluoxetine for a total of 14 days, after a period of mild depression. Although far from being perfectly stable, I was still an energetic, passionate, intelligent young man with big aspirations and a lot to live for. Those 14 pills changed all of that. After about a week on the m
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
DESVENLAFAXINE is a SNRI, while FLUOXETINE belongs to the SSRI class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
Both medications are approved for See full prescribing information. When two drugs treat the same condition, the choice between them often depends on the patient's medical history, other medications, tolerability, and prescriber preference.
DESVENLAFAXINE carries 4 FDA warnings. FLUOXETINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.