Donanemab vs Lecanemab

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*TLDR: Cassava’s Simufilam (NASDAQ:SAVA) is the only treatment ever shown in U.S. clinical trials to actually help Alzheimer's cognition over time and it’s desperately needed as 1 in 3 Americans die with dementia and Alz is the sixth leading cause of death. I just bet $25M in Cassava because it is

* Cassava Sciences (SAVA) may have the first truly efficacious drug for Alzheimer’s Disease (AD) in Simufilam, although currently their science, clinical results, and integrity are under constant attack. * Despite the best efforts of short sellers to discredit the company, we believe the FDA will no

For more of my analysis daily, including stock specific research and interpretation of the data, please join r/Tradingedge **ANALYSIS:** * I will update on CPI expectations during the day. * Possibly seeing a short term top on SPX now, so some movement lower, before next push higher. * Not expect

We just got back from speaking to a Neurologist at UCSF to start my mom on Donanemab and I just wanted to share a few key points for anyone considering transfusion therapies. There’s been a lot of misinformation in regards to Amyloid plaques and the recent NYT article doesn’t help. First and foremo

hi everyone, I'm looking to understand what are the screening and treatment options for my mother. She has been showing signs of neurodegeneration increasingly and I look to convince her to seek early screening and detection, and to reassure her I would like to be able to explain her options to her.

Has anyone under gone Donanemab or Lecanemab treatments? My mom is 77 and suffering from mild/moderate cognitive impairment. She was diagnosed this year with Alzheimer's based on a PET scan and the ptau blood test. Her neurologist is recommending Donanemab infusions. I'm curious if anyone has underg

Hello, we recently found out my mom would be able to take Anti-Amyloid Therapy medication. We originally were told she was too far along by the people who diagnosed her with early onset, so that was surprising news to hear! I’ve been reading over pamphlets my step dad sent and I was just curious if

Mahesh Narayan, a biophysicist and professor at the University of Texas at El Paso, envisions a day when a truck from a lab might back into a parking spot behind the local Starbucks in service of treating Parkinson’s disease. Recent studies have demonstrated a correlation between drinking coffee and

👉 **TL;DR: This post is just the long—really long—and winding rant of a guy with a dog.** **Avoid reading this and go enjoy your life doing something else instead.** ​ **LCID starts to move.** Today, LCID started to move at 12:20 EST. Twenty-three minutes later, the reason surfaced:

**This is a re-post from my blog.** My first Lecanemab infusion was October 28, 2025. My tenth was February 17, 2026. The most frustrating part of Lecanemab treatment is not knowing if it is helping me. Is Lecanemab slowing the progression of my Alzheimer’s disease? I have no idea, and neither does

I published the following to my blog today: Last week, at the 2026 International Conference on Alzheimer's and Parkinson's Diseases, Eisai presented new real-world findings on the long-term usage of Lecanemab. Analyzing data from the [PurpleLab claims database](https://info.purplelab.com/clear-claim

Can someone convince me that Leqembi is actually a significant advancement in Alzheimer’s treatment? I admit to my ignorance in pharmacology, and I haven’t seen any legitimate articles on the drug. Therefore I’m trying to be very open minded if someone gives me an educated response. To me, Leqembi