Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare FLUOXETINE (Fluoxetine) and Levomilnacipran (Fetzima) — clinical data, side effects, and patient experiences.
Fluoxetine, Prozac · SSRI
How it works
12.1 Mechanism of Action Although the exact mechanism of fluoxetine is unknown, it is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin.
Approved for
Fetzima · SNRI
How it works
SNRI with preferential norepinephrine reuptake inhibition over serotonin, providing antidepressant and functional improvement effects.
Approved for
Estimated frequency (%) based on clinical trial data
No specific warnings
Based on 19 Reddit discussions
FLUOXETINE
38%
positive
13 threads
Levomilnacipran
50%
positive
6 threads
% of discussions mentioning each side effect
13 Reddit threads analysed for FLUOXETINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
185 upvotes
Most discussed side effects in community
I am depression. The person I used to be is gone, there is no going back from this. I'm just sat In the hospital while my mum speaks to cahms, trying to hide my neck from all the other patients. I'm desperate to leave the hospital and get home but I know I'm gonna try again eventually. I've been on
Started seeing a therapist in April 2013 because my mum was worried about me. The therapist was in her mid 20's, and was pretty, so I felt a level of attraction to her, and told her a lot of things about me that I hadn't told anyone. I was in high school at the time, an all boys one, so she was basi
Hello everyone, my name is Samuel, I'm 14 years old and I'm Brazilian. I've been having these thoughts for about two or three years, but in the last few days they've gotten a lot worse. especially after I started taking fluoxetine I think about suicide all day and it haunts me all the time, I can'
I feel like the anti-anxiety effects of this drug (Fluoxetine AKA Prozax), which have been good in a lot of ways, have caused me to lose a certain sense of 'urgency' or 'appropriate' anxiety towards things like academic deadlines etc. Things I really should be worrying about don't really make me anx
Hi! hope someone who is not feeling good read this. I tried to commit suicide two years ago. in fact, using another reddit account I found help with this community before, and people was really nice!.. So now I want to write this just to i dunno... maybe put some hope in at least someone. I've bee
A brief summary: so I had major depression & severe for anxiety for about 1.5yrs, it was serious & I was at an all time low, hospital admissions, the lot. Doctors suspected it was drug induced (from MDMA), which I completely agree with, it was the time I spiralled down HARD, and also situati
I am on 20mg of fluoxetine and it’s stopping me from crying almost completely, I can occasionally squeeze out a tear or two and I’ve had one been breakdown when I was drunk but other than that the feelings build in my body and I feel worse and worse but it has nowhere to go. I’m also breaking out in
7 months ago, I took fluoxetine for a total of 14 days, after a period of mild depression. Although far from being perfectly stable, I was still an energetic, passionate, intelligent young man with big aspirations and a lot to live for. Those 14 pills changed all of that. After about a week on the m
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
6 Reddit threads analysed for Levomilnacipran
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
14 upvotes
Most discussed side effects in community
I took a Genetic Test called Genesight and it listed the following medicines to use as directed (highlighted in green) but I don't think any of them are for OCD. Does anyone have experience taking any of these medicines specifically for OCD? * bupropion (Wellbutrin®) * desipramine (Norpramin®) * des
I wanted to share my experience with Viibryd thus far, since when I first starting looking into it after being prescribed it, I mostly found people saying how they had a bad time on it. Quick background, this is the 6th antidepressant I've tried. Before Viibryd, I was on citalopram for 8 years and
**Most Common Antidepressants** * *SSRI's* \- Works on Serotonin * Sertraline (Zoloft) * Fluoxetine (Prozac) * Paroxetine (Paxil) * Citalopram (Celexa) * Escitalopram (Lexapro) * Fluvoxamine (Luvox) * Trazodone (Desyrel) * Vilazodone (Viibryd) * Vortioxetine (Trintellix)
I'm really struggling with my depression post-surgery. I think a big part of the problem may be my anti-depressant. I have had great success with Fetzima/levomilnacipran, a little-used antidepressant that unfortunately, ONLY comes in an extended release version. I think that, with my rny and shorte
Apologies for the wall of text - I've done my best to condense 15 years of crap into a reasonably sized post. ​ I have a depressive disorder. This much is obvious. I've been on antidepressants for 15 years. I've tried 6 of them in total (fluoxetine, sertraline, trazodone, bupropion, vilaz
Hello, I'm am getting off Wellbutrin, and want to research an alternative drug to ask my DOC about. This is for MDD, and this is what I found: Lexapro - escitalopram (SSRI, seems fine, side effects don't sound good.) Venlafaxine-Effexor (SNRI, similar to Wellbutrin, standard SNRI side effects)) Dul
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
FLUOXETINE is a SSRI, while Levomilnacipran belongs to the SNRI class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
FLUOXETINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.