Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare GLIPIZIDE (Glipizide) and INSULIN DEGLUDEC (Tresiba) — clinical data, side effects, and patient experiences.
Glipizide, Glucotrol · Sulfonylurea
How it works
Mechanism of Action The primary mode of action of glipizide in experimental animals appears to be the stimulation of insulin secretion from the beta cells of pancreatic islet tissu...
Approved for
Tresiba · Insulin
How it works
12.1 Mechanism of Action The primary activity of insulin, including TRESIBA, is regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating periphe...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 17 Reddit discussions
GLIPIZIDE
40%
positive
15 threads
INSULIN DEGLUDEC
0%
positive
2 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for GLIPIZIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
88 upvotes
Most discussed side effects in community
Just wanted to share some great news. My grandfather had diabetes and even had to have his leg amputated later in life. I watched growing up how restrictive his diet was. My father and brother were also diagnosed later. 2 years ago, after thinking I had restless leg syndrome, I got a blood test
My A1c results after four months of carb reduction, intermittent fasting, apple cider vinegar, cardio and a 60lbs weight loss... 5.4%! Plus Metformin, Glipizide and ~~Trulicity~~\*. Hoping to be able to decrease the meds and hopefully not have to start insulin. My a1c was previously > 11, thankf
For the first time since I started getting my A1C checked regularly, it is now in normal range! I got my recent labs back, and it was 5.7. It was as high as 11.7 as late as two years ago, and has regularly been in the 8+ range for several years. in July, it was 6.7. It has taken a combination of Met
6 months ago, after complaining of hypos in the middle of the night from Glipizide, my doctor took me off of it and put me on Mounjaro. I've been steadily increasing my dosage every few months and am up to 10mg now. He told me that I wouldn't need to check my glucose more than once a day which signi
1/ yes, I know, there's room for improvement. That's always going to be true. I'm okay with being a work in progress. :) 2/ I started off 14++ earlier this year and my PCP stressed the need for a gentle slope of reduction in sugars so complications wouldn't plague me as much. 3/ I started off with
January 31, I had an A1c of 12.4. My endo wanted to start me on insulin, but I decided I was going to try to take control of the factors that I knew I was not paying attention to. Revamped my diet, cut calories, slowly incorporated exercise, filled the nutritional gaps I needed with supplements, and
Back in October my a1c was 11.6 yesterday got my new results for my a1c and I'm at 8.4 I need to tell someone that understands me and that is you guys.i have just been taking all my medications i take metformin 1000 and glipizide 10 mg and I stopped eating late at night and stopped all the soft drin
EDIT: I realized that I put 5.7 in the title. It's actually 5.4. Just want to share my story because the last three months has been a roller coaster both physically and mentally. Hopefully this helps for those who needs guidance. I [29M] was diagnosed August of this year with an A1C of 11.5 with a f
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
2 Reddit threads analysed for INSULIN DEGLUDEC
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
32 upvotes
Have any other independent pharms/techs noticed a sudden drop in reimbursement rates on brand names, predominantly from Cigna plans? Of course we would always lose money on 90 day supplies, but we would at least be close to our cost, maybe losing $5-20$ on 30-days. However, in the past 48 ours I hav
Wellcare will not pay for brand name Tresiba in 2025. However, they will pay for insulin degludec (unbranded biologic version of Tresiba). Insulin deludec is of course on backorder. WellCare already denied the prior auth for name brand. Their other option on formulary insulin glargine-yfgn is also o
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
GLIPIZIDE is a Sulfonylurea, while INSULIN DEGLUDEC belongs to the Insulin class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. GLIPIZIDE is administered via Oral, whereas INSULIN DEGLUDEC uses Subcutaneous. Route of administration can affect onset of action and patient adherence.
GLIPIZIDE carries 4 FDA warnings. INSULIN DEGLUDEC carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.