Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare Hydroxychloroquine (Plaquenil) and UPADACITINIB (Rinvoq) — clinical data, side effects, and patient experiences.
Plaquenil · DMARD
How it works
Accumulates in lysosomes, raising pH and inhibiting antigen processing and presentation. Reduces T-cell activation and cytokine production.
Approved for
Rinvoq · JAK Inhibitor
How it works
12.1 Mechanism of Action Upadacitinib is a Janus kinase (JAK) inhibitor. JAKs are intracellular enzymes which transmit signals arising from cytokine or growth factor-receptor inter...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 24 Reddit discussions
Hydroxychloroquine
0%
positive
9 threads
UPADACITINIB
60%
positive
15 threads
% of discussions mentioning each side effect
9 Reddit threads analysed for Hydroxychloroquine
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
310 upvotes
Most discussed side effects in community
It's amazing how many people suddenly have Rheumatoid Arthritis! Upon receipt of all Plaquenil scripts, I am verifying with the prescriber an on-label indication. I am informing prescriber and patient that if this is fraudulent, I will file a Board of Medicine complaint against the prescriber, and t
Raised. EDIT:🙋♂️✋🤚🙌
Going to be a lot of these in the coming days I'm sure. You know what's really galling about hydroxychloroquine being on back order? The thing that really makes me angry? Not a single prescriber that has called me (and they ask for me specifically) has called asking if we have the drug for their pat
Is anybody else in the retail world starting to see a suspiciously high number of Ivermectin scripts all of a sudden?? Is this the next Hydroxychloroquine of 2020?
Had a doctor call in #180 for their entire family. He’s an eye doctor and it is clearly outside of his scope of practice. I’m an intern and none of my pharmacists know how to report it.
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for UPADACITINIB
Overall Sentiment
Slightly positive
Comparison Threads
0
Avg Post Score
29 upvotes
Most discussed side effects in community
For context: for pretty much all of last year over 80% of my body was covered in eczema rash. It was so severe I couldn't use the shower and had to either take baths or wash myself in the sink. My scalp was constantly peeling and I was *always* itchy. While my skin would get better in summer, it was
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Hey everyone! I just wanted to provide some sort of update having been on Upadacitinib for just over a month. My eczema is gone and I no longer need to take cold showers and I don't even need to moisturise after showers. My skin looks healthy and clear it is so surreal. This medication is not a ste
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I am interested in participating in a clinical trial. I am leaning towards the 3 mentioned in the title, though I would love to hear about any others that seem promising. I am hoping there will be phase 3 trials in my area some time in the first half of 2018 for ABT-494 and PF-04965842. Phase 3 for
About 80% of my body was covered when I went to the dermatologist, so he sent me to hospital for inpatient treatment for 5 days. I did a paraffin bath -> topical steroid -> wet wrap -> emollient treatment twice a day and everything has cleared up. I've been given a metric tonne of moisturiz
Almost a year ago, after years of worsening Atopic Dermatitis, i said enough is enough, and decided to buy Upadacitinib, a JAK inhibitor originally used for rheumatoid arthritis, after reading about very promising clinical trials for AD. When i posted about it many of you guys were surprised about
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Hydroxychloroquine is a DMARD, while UPADACITINIB belongs to the JAK Inhibitor class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
Hydroxychloroquine carries 3 FDA warnings. UPADACITINIB carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.