Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare INSULIN DEGLUDEC (Tresiba) and PIOGLITAZONE (Pioglitazone) — clinical data, side effects, and patient experiences.
Tresiba · Insulin
How it works
12.1 Mechanism of Action The primary activity of insulin, including TRESIBA, is regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating periphe...
Approved for
Pioglitazone, Actos, Actoplus Met · Thiazolidinedione
How it works
12.1 Mechanism of Action Pioglitazone is a thiazolidinedione that depends on the presence of insulin for its mechanism of action. Pioglitazone decreases insulin resistance in the p...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 17 Reddit discussions
INSULIN DEGLUDEC
0%
positive
2 threads
PIOGLITAZONE
40%
positive
15 threads
% of discussions mentioning each side effect
2 Reddit threads analysed for INSULIN DEGLUDEC
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
32 upvotes
Have any other independent pharms/techs noticed a sudden drop in reimbursement rates on brand names, predominantly from Cigna plans? Of course we would always lose money on 90 day supplies, but we would at least be close to our cost, maybe losing $5-20$ on 30-days. However, in the past 48 ours I hav
Wellcare will not pay for brand name Tresiba in 2025. However, they will pay for insulin degludec (unbranded biologic version of Tresiba). Insulin deludec is of course on backorder. WellCare already denied the prior auth for name brand. Their other option on formulary insulin glargine-yfgn is also o
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for PIOGLITAZONE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
25 upvotes
Most discussed side effects in community
I was Diagnosed 7 months ago. I'm 5'7", and I weighed 260 lbs (Obese Class III). Lab results showed: * A1C of 11.2 * non alcoholic fatty liver * high blood pressure (hypertension stage 2) * high cholesterol I was prescribed Mounjaro, pioglitazone, amlodipine, and rosuvastatin. At my follow up appoin
Was diagnosed type-2 on November 11th, which was the first day I tested. My very first test was above 280. I made a post here a few weeks ago that my highest was 380. After that, I made an aggressive change to my diet(Tuna mixes with veggies and a bit of cream cheese on low carb wraps are god like),
been on insulin for 6 month . i turned my health around in a short time 12.9 a1c to 5.4 a1c ( made a post a month ago about that ). well at today check up docotor said i can fully stop all insulin and just keep taking metformin and Pioglitazone and i no longer need to come back in every 3 months
Hi I’m Rosa and I don’t know what I’m doing, Ok back story as concise as I can: -When I was 15 in was diagnosed with PCOS and was told that I would have insulin resistance because of it. -I was put on metformin to help with it but I can’t tolerate it, I’m constantly sick to my stomach on it -
I'm already down to 6.0. A 3.5% drop. Like I'm right at the cusp of being at the finish line (I know it's not the end, and that I have to stay there) of getting out of the "Complication Range" Went from a dangerous level down to the middle of Pre-diabetic in only 3 months. Also, my average, if going
I've been diabetic ever since I had my son 3 years ago. I'm the type that has no clue when my BS is running high; I can only ever tell when it's low, but that hasn't happened in a while. I know I need to get my shit together and work on reversing this but it's so hard. I'm not sure why it's so hard
On January 19 I was tested by my doctor and confirmed I was t2 diabetic with an a1c of 10.4. I just got my lab results from the blood test on April 21, that my a1c is now 5.3!!!!!!! I didn't just diet - I made a life change. I worked with a nutritionalist, counted carbs and proteins, cooked every m
Disclaimer: I’m not looking for medical advice. I’m aware information contained in this post does not give anyone enough information for any kind of diagnosis. 54 y/o male, 5’7”, SW 260, CW 228. Three months ago I had my first doctor’s appointment in 7 years. My A1C results were bad (11.2%), and I
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
INSULIN DEGLUDEC is a Insulin, while PIOGLITAZONE belongs to the Thiazolidinedione class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. INSULIN DEGLUDEC is administered via Subcutaneous, whereas PIOGLITAZONE uses Oral. Route of administration can affect onset of action and patient adherence.
Both medications are approved for See full prescribing information. When two drugs treat the same condition, the choice between them often depends on the patient's medical history, other medications, tolerability, and prescriber preference.
INSULIN DEGLUDEC carries 4 FDA warnings. PIOGLITAZONE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.