Compare INSULIN DEGLUDEC (Tresiba) and Semaglutide (Ozempic) — clinical data, side effects, and patient experiences.
Tresiba · Insulin
How it works
12.1 Mechanism of Action The primary activity of insulin, including TRESIBA, is regulation of glucose metabolism. Insulin and its analogs lower blood glucose by stimulating periphe...
Approved for
Ozempic, Wegovy, Rybelsus · GLP-1 Agonist
How it works
Glucagon-like peptide-1 (GLP-1) receptor agonist with 94% homology to human GLP-1. Stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite c...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 13 Reddit discussions
INSULIN DEGLUDEC
0%
positive
2 threads
Semaglutide
36%
positive
11 threads
% of discussions mentioning each side effect
2 Reddit threads analysed for INSULIN DEGLUDEC
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
32 upvotes
Have any other independent pharms/techs noticed a sudden drop in reimbursement rates on brand names, predominantly from Cigna plans? Of course we would always lose money on 90 day supplies, but we would at least be close to our cost, maybe losing $5-20$ on 30-days. However, in the past 48 ours I hav
Wellcare will not pay for brand name Tresiba in 2025. However, they will pay for insulin degludec (unbranded biologic version of Tresiba). Insulin deludec is of course on backorder. WellCare already denied the prior auth for name brand. Their other option on formulary insulin glargine-yfgn is also o
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
11 Reddit threads analysed for Semaglutide
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
30 upvotes
Most discussed side effects in community
I was diagnosed back at the end of March this year and I was very sick. My A1C was 14! Blood sugars of 300+ average. I took this very seriously as I had seen what type 1 did to my grandma. And I know type 1 and type 2 are two very different beasts, I did not want to have to give myself insulin as we
I am new diagnosed type 2 diabetic. My fasting bs was 140 and A1C is 6.4. My insurance denied both tirzepitide and Semaglutide brand names stating my A1C must be 6.5. I’m so frustrated. I had started taking compounded Semaglutide prior to my diagnosis for weight loss and then did my blood work and r
**1st June 2021 - new docs, start treatment** weight: **216 lb** / 97.98 kg height: 6'1" / 1.85 m BMI: 28.5 (overweight) BP: **132/90** (too high) *start lisinopril* HbA1c: **10.4%** average BG: 252 mg/dL, 14 mmol/L LDL: 127 mg/dL HDL: 36 mg/dL TG: 845 mg/dL (!)
I have been using ozempic for 3 months. My side effects were mild and bearable. I noticed that I got nausea when I ate unhealthy or large amounts of food. I started to eat less and better quality. I was more sensitive to motion nausea (like long bus rides), but all ok. Last month my period was
I was diagnosed with T2 in April 2024 after having symptoms like thirsty and weight loss . My A1C was 11.5 in April .after taking medications and vigorous workouts , A1C dropped to 5.5 in October . I trained for marathon and ran Chicago marathon . I put in lot of miles . I am not strict on diet tho
Well... I had a good run, but Ozempic has finally become Unobtainium where I live, and my endo seems intent on waiting a couple of days to get back to me to say that they sent a refill to a pharmacy that doesn't have it to sell. I'm supposed to take a 2 mg shot today, and my next endo appointment is
Hi guys, Happy New Year! I was diagnosed with T2 about a year ago, but I struggled taking care of myself. I was depressed and didn't really think about it too much, therefore, I was still eating a lot of junk food, staying all day in the couch but I was always feeling tired and my health wasn't the
Hi everyone. My husband (33) was recently diagnosed with type 2 diabetes and I am a feeling a broad mix of emotions. We got married this year, I'm a deeply anxious person, and it just made me jump straight to worst case scenarios. So it's been a hard couple of days and I don't think I'm making it an
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
INSULIN DEGLUDEC is a Insulin, while Semaglutide belongs to the GLP-1 Agonist class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. INSULIN DEGLUDEC is administered via Subcutaneous, whereas Semaglutide uses Subcutaneous or Oral. Route of administration can affect onset of action and patient adherence.
INSULIN DEGLUDEC carries 4 FDA warnings. Semaglutide carries 3 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.