Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare LIRAGLUTIDE (Liraglutide) and ORLISTAT (Xenical) — clinical data, side effects, and patient experiences.
Liraglutide, Victoza, Saxenda · GLP-1 Agonist
How it works
12.1 Mechanism of Action Liraglutide is an acylated human GLP-1 receptor agonist with 97% amino acid sequence homology to endogenous human GLP-1(7 to 37). GLP-1(7 to 37) represents...
Approved for
Xenical · Weight Management
How it works
12.1 Mechanism of Action Orlistat is a reversible inhibitor of gastrointestinal lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by formi...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 22 Reddit discussions
LIRAGLUTIDE
27%
positive
15 threads
ORLISTAT
29%
positive
7 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for LIRAGLUTIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
9 upvotes
Most discussed side effects in community
After two consecutive blood tests showed and A1C of 4.5-4.6, my primary care physician had me drop my T2 meds. I achieved these results through diet and exercise, supported by my meds. First he had me drop Jardiance, and that went fine. Another 4.6 A1C. Then he had me drop Victoza/Liraglutide and Me
Slight cross post from a r/KaiserPermanente thread of mine. After 2 years and 4 denials to see an endocrinologist as an uncontrolled T2D, I finally got them to accept the referral after asking for a formal denial letter so I could go self-pay to an out of network hospital system a few counties away.
I was diagnosed with T2 back in November and it gave me a scare. I’m in the morbidly obese category and on liraglutide to help. I don’t think it’s working well for me but that’s a separate issue. I feel like I need another kick, I haven’t received a lot of support from my GP (in the UK) and I am try
What do you guys usually do with leftover medication? This is 0.5mg and based on my usual dosage of 1.8mg/day, I rarely have enough extra across 3 sticks to constitute one last dose at the end of the medication period. Do you still use the extra?
Hi all I’ve been diagnosed type 2 this January and have since been on a mix of metformin, glimepiride, and sitagliptin none of which lowered my sugars very much. My nurse has suggested that I could go onto a daily or weekly injection (Liraglutide/Trulicity) to help stimulate the insulin levels. Does
When I was first diagnosed, I couldn’t afford my medications to keep everything maintained. My A1C is sitting somewhere around a 7/8. Two years later, I moved to 12u long acting and around 20-30u of fast acting. Doctor tried to put me on Ozempic, but I ended up in the ER from an allergic reaction.
For the past 5 months I have been working really hard on my diet and fitness level where i've pretty much got it in lock down. I've integrated healthy eating and going into the gym in a very sustainable way where it's a part of me now. It is kind of surreal to think now there were days on end I woul
It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Liraglutide injection also slows the emptying of the stomach and may decrease appetite and cause weight loss. It's been a couple of days and I'm having some trouble with nausea. I've found that
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
7 Reddit threads analysed for ORLISTAT
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
267 upvotes
Most discussed side effects in community
I'm 20F, 5' 9" (175cm). SW255, CW140, GW140. So a couple of years ago my doctor suggested that I do a low-fat diet with 6-7 small 250cal meals per day, basing them on whole grains and some very lean protein with a fruit, and taking orlistat with meals that had more fat than usual. I tried that and f
I wanted to share my experience in case it helps anyone fighting with their insurance or pharmacy benefit manager (PBM) to get coverage for **Mounjaro or Zepbound**. I’m a **Massachusetts resident (47F, 5’6”) with a BMI of 37.1 in 9/2022**. I have **hypertension and moderate sleep apnea (AHI=15)**,
This sub has been a huge source of info. and comfort to me and I wanted to share my story in case it may help those considering Sema for weight loss: I started on Sema for "vanity" reasons. I have struggled with a borderline ED and body dysmorphia all my life, having grown up a as a dancer without
I read so much negative stuff about orlistat on this forum and elsewhere, and thought I should take time to share my experience. A lot people describe an uneasy feeling in their stomach when eating fat on orlistat. I do have *a *feeling too, but I don't think it's uncomfortable. I just feel... satia
Greetings, Long time lurker, v. rare poster. Came here because I was prescribed Orlistat, got the dreaded oily diarrhea, scoured the internet for answers to no avail and eventually found a solution myself. I reckon reddit is the best possible place to put this info for any other poor souls scourin
Hi everyone. I am mainly writing this for cathartic reasons. I have struggled with weight my entire life and I never feel like talking to my friends or tweeting about it quite captures my life. I welcome any comments, criticisms, or words of support. ​ TLDR: I'm a smart guy and have had s
Another struggling to lose weight with pcos post! I exercise regularly - bike to the gym in the morning, yoga or dance in my lunch break and some kind of activity at night like swimming or walking. My eating habits are pretty good - healthy home prepared meals. I try to be mindful of carbs and sug
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
LIRAGLUTIDE is a GLP-1 Agonist, while ORLISTAT belongs to the Weight Management class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. LIRAGLUTIDE is administered via Subcutaneous, whereas ORLISTAT uses Oral. Route of administration can affect onset of action and patient adherence.
LIRAGLUTIDE carries 4 FDA warnings. ORLISTAT carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.