Medical Disclaimer: This site provides informational comparisons only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or pharmacist before making medication decisions.
Compare LIRAGLUTIDE (Liraglutide) and PIOGLITAZONE (Pioglitazone) — clinical data, side effects, and patient experiences.
Liraglutide, Victoza, Saxenda · GLP-1 Agonist
How it works
12.1 Mechanism of Action Liraglutide is an acylated human GLP-1 receptor agonist with 97% amino acid sequence homology to endogenous human GLP-1(7 to 37). GLP-1(7 to 37) represents...
Approved for
Pioglitazone, Actos, Actoplus Met · Thiazolidinedione
How it works
12.1 Mechanism of Action Pioglitazone is a thiazolidinedione that depends on the presence of insulin for its mechanism of action. Pioglitazone decreases insulin resistance in the p...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 30 Reddit discussions
LIRAGLUTIDE
27%
positive
15 threads
PIOGLITAZONE
40%
positive
15 threads
% of discussions mentioning each side effect
15 Reddit threads analysed for LIRAGLUTIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
9 upvotes
Most discussed side effects in community
After two consecutive blood tests showed and A1C of 4.5-4.6, my primary care physician had me drop my T2 meds. I achieved these results through diet and exercise, supported by my meds. First he had me drop Jardiance, and that went fine. Another 4.6 A1C. Then he had me drop Victoza/Liraglutide and Me
Slight cross post from a r/KaiserPermanente thread of mine. After 2 years and 4 denials to see an endocrinologist as an uncontrolled T2D, I finally got them to accept the referral after asking for a formal denial letter so I could go self-pay to an out of network hospital system a few counties away.
I was diagnosed with T2 back in November and it gave me a scare. I’m in the morbidly obese category and on liraglutide to help. I don’t think it’s working well for me but that’s a separate issue. I feel like I need another kick, I haven’t received a lot of support from my GP (in the UK) and I am try
What do you guys usually do with leftover medication? This is 0.5mg and based on my usual dosage of 1.8mg/day, I rarely have enough extra across 3 sticks to constitute one last dose at the end of the medication period. Do you still use the extra?
Hi all I’ve been diagnosed type 2 this January and have since been on a mix of metformin, glimepiride, and sitagliptin none of which lowered my sugars very much. My nurse has suggested that I could go onto a daily or weekly injection (Liraglutide/Trulicity) to help stimulate the insulin levels. Does
When I was first diagnosed, I couldn’t afford my medications to keep everything maintained. My A1C is sitting somewhere around a 7/8. Two years later, I moved to 12u long acting and around 20-30u of fast acting. Doctor tried to put me on Ozempic, but I ended up in the ER from an allergic reaction.
For the past 5 months I have been working really hard on my diet and fitness level where i've pretty much got it in lock down. I've integrated healthy eating and going into the gym in a very sustainable way where it's a part of me now. It is kind of surreal to think now there were days on end I woul
It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Liraglutide injection also slows the emptying of the stomach and may decrease appetite and cause weight loss. It's been a couple of days and I'm having some trouble with nausea. I've found that
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
15 Reddit threads analysed for PIOGLITAZONE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
25 upvotes
Most discussed side effects in community
I was Diagnosed 7 months ago. I'm 5'7", and I weighed 260 lbs (Obese Class III). Lab results showed: * A1C of 11.2 * non alcoholic fatty liver * high blood pressure (hypertension stage 2) * high cholesterol I was prescribed Mounjaro, pioglitazone, amlodipine, and rosuvastatin. At my follow up appoin
Was diagnosed type-2 on November 11th, which was the first day I tested. My very first test was above 280. I made a post here a few weeks ago that my highest was 380. After that, I made an aggressive change to my diet(Tuna mixes with veggies and a bit of cream cheese on low carb wraps are god like),
been on insulin for 6 month . i turned my health around in a short time 12.9 a1c to 5.4 a1c ( made a post a month ago about that ). well at today check up docotor said i can fully stop all insulin and just keep taking metformin and Pioglitazone and i no longer need to come back in every 3 months
Hi I’m Rosa and I don’t know what I’m doing, Ok back story as concise as I can: -When I was 15 in was diagnosed with PCOS and was told that I would have insulin resistance because of it. -I was put on metformin to help with it but I can’t tolerate it, I’m constantly sick to my stomach on it -
I'm already down to 6.0. A 3.5% drop. Like I'm right at the cusp of being at the finish line (I know it's not the end, and that I have to stay there) of getting out of the "Complication Range" Went from a dangerous level down to the middle of Pre-diabetic in only 3 months. Also, my average, if going
I've been diabetic ever since I had my son 3 years ago. I'm the type that has no clue when my BS is running high; I can only ever tell when it's low, but that hasn't happened in a while. I know I need to get my shit together and work on reversing this but it's so hard. I'm not sure why it's so hard
On January 19 I was tested by my doctor and confirmed I was t2 diabetic with an a1c of 10.4. I just got my lab results from the blood test on April 21, that my a1c is now 5.3!!!!!!! I didn't just diet - I made a life change. I worked with a nutritionalist, counted carbs and proteins, cooked every m
Disclaimer: I’m not looking for medical advice. I’m aware information contained in this post does not give anyone enough information for any kind of diagnosis. 54 y/o male, 5’7”, SW 260, CW 228. Three months ago I had my first doctor’s appointment in 7 years. My A1C results were bad (11.2%), and I
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
LIRAGLUTIDE is a GLP-1 Agonist, while PIOGLITAZONE belongs to the Thiazolidinedione class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles. LIRAGLUTIDE is administered via Subcutaneous, whereas PIOGLITAZONE uses Oral. Route of administration can affect onset of action and patient adherence.
Both medications are approved for See full prescribing information. When two drugs treat the same condition, the choice between them often depends on the patient's medical history, other medications, tolerability, and prescriber preference.
LIRAGLUTIDE carries 4 FDA warnings. PIOGLITAZONE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.