Compare LIRAGLUTIDE (Liraglutide) and Semaglutide (Ozempic) — clinical data, side effects, and patient experiences.
Liraglutide, Victoza, Saxenda · GLP-1 Agonist
How it works
12.1 Mechanism of Action Liraglutide is an acylated human GLP-1 receptor agonist with 97% amino acid sequence homology to endogenous human GLP-1(7 to 37). GLP-1(7 to 37) represents...
Approved for
Ozempic, Wegovy, Rybelsus · GLP-1 Agonist
How it works
Glucagon-like peptide-1 (GLP-1) receptor agonist with 94% homology to human GLP-1. Stimulates insulin secretion, suppresses glucagon, slows gastric emptying, and reduces appetite c...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 25 Reddit discussions
LIRAGLUTIDE
21%
positive
14 threads
Semaglutide
36%
positive
11 threads
% of discussions mentioning each side effect
14 Reddit threads analysed for LIRAGLUTIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
9 upvotes
Most discussed side effects in community
After two consecutive blood tests showed and A1C of 4.5-4.6, my primary care physician had me drop my T2 meds. I achieved these results through diet and exercise, supported by my meds. First he had me drop Jardiance, and that went fine. Another 4.6 A1C. Then he had me drop Victoza/Liraglutide and Me
Slight cross post from a r/KaiserPermanente thread of mine. After 2 years and 4 denials to see an endocrinologist as an uncontrolled T2D, I finally got them to accept the referral after asking for a formal denial letter so I could go self-pay to an out of network hospital system a few counties away.
I was diagnosed with T2 back in November and it gave me a scare. I’m in the morbidly obese category and on liraglutide to help. I don’t think it’s working well for me but that’s a separate issue. I feel like I need another kick, I haven’t received a lot of support from my GP (in the UK) and I am try
Hi all I’ve been diagnosed type 2 this January and have since been on a mix of metformin, glimepiride, and sitagliptin none of which lowered my sugars very much. My nurse has suggested that I could go onto a daily or weekly injection (Liraglutide/Trulicity) to help stimulate the insulin levels. Does
When I was first diagnosed, I couldn’t afford my medications to keep everything maintained. My A1C is sitting somewhere around a 7/8. Two years later, I moved to 12u long acting and around 20-30u of fast acting. Doctor tried to put me on Ozempic, but I ended up in the ER from an allergic reaction.
For the past 5 months I have been working really hard on my diet and fitness level where i've pretty much got it in lock down. I've integrated healthy eating and going into the gym in a very sustainable way where it's a part of me now. It is kind of surreal to think now there were days on end I woul
It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Liraglutide injection also slows the emptying of the stomach and may decrease appetite and cause weight loss. It's been a couple of days and I'm having some trouble with nausea. I've found that
Hey everyone. Quick disclaimer that I do not have T2D (though was pre-T2D a few years ago). I understand that internet advice cannot substitute for medical professionals' words, but I was hoping if others in /r/diabetes have had success with dealing with a situation like my father's. He was diagnos
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
11 Reddit threads analysed for Semaglutide
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
30 upvotes
Most discussed side effects in community
I was diagnosed back at the end of March this year and I was very sick. My A1C was 14! Blood sugars of 300+ average. I took this very seriously as I had seen what type 1 did to my grandma. And I know type 1 and type 2 are two very different beasts, I did not want to have to give myself insulin as we
I am new diagnosed type 2 diabetic. My fasting bs was 140 and A1C is 6.4. My insurance denied both tirzepitide and Semaglutide brand names stating my A1C must be 6.5. I’m so frustrated. I had started taking compounded Semaglutide prior to my diagnosis for weight loss and then did my blood work and r
**1st June 2021 - new docs, start treatment** weight: **216 lb** / 97.98 kg height: 6'1" / 1.85 m BMI: 28.5 (overweight) BP: **132/90** (too high) *start lisinopril* HbA1c: **10.4%** average BG: 252 mg/dL, 14 mmol/L LDL: 127 mg/dL HDL: 36 mg/dL TG: 845 mg/dL (!)
I have been using ozempic for 3 months. My side effects were mild and bearable. I noticed that I got nausea when I ate unhealthy or large amounts of food. I started to eat less and better quality. I was more sensitive to motion nausea (like long bus rides), but all ok. Last month my period was
I was diagnosed with T2 in April 2024 after having symptoms like thirsty and weight loss . My A1C was 11.5 in April .after taking medications and vigorous workouts , A1C dropped to 5.5 in October . I trained for marathon and ran Chicago marathon . I put in lot of miles . I am not strict on diet tho
Well... I had a good run, but Ozempic has finally become Unobtainium where I live, and my endo seems intent on waiting a couple of days to get back to me to say that they sent a refill to a pharmacy that doesn't have it to sell. I'm supposed to take a 2 mg shot today, and my next endo appointment is
Hi guys, Happy New Year! I was diagnosed with T2 about a year ago, but I struggled taking care of myself. I was depressed and didn't really think about it too much, therefore, I was still eating a lot of junk food, staying all day in the couch but I was always feeling tired and my health wasn't the
Hi everyone. My husband (33) was recently diagnosed with type 2 diabetes and I am a feeling a broad mix of emotions. We got married this year, I'm a deeply anxious person, and it just made me jump straight to worst case scenarios. So it's been a hard couple of days and I don't think I'm making it an
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
Both LIRAGLUTIDE and Semaglutide belong to the GLP-1 Agonist class. While they share a similar mechanism of action, differences in pharmacokinetics, dosing, and side effect profiles may make one more suitable than the other for individual patients. LIRAGLUTIDE is administered via Subcutaneous, whereas Semaglutide uses Subcutaneous or Oral. Route of administration can affect onset of action and patient adherence.
LIRAGLUTIDE carries 4 FDA warnings. Semaglutide carries 3 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.