MESALAMINE vs UPADACITINIB

***Guide to beating Severe IBS-D in America*** There are a lot of resources/posts on IBS-C on this subreddit, so I wanted to post something for us IBS-D sufferers. Here’s steps I, as a non-physician and very severe IBS-D sufferer, recommend to hopefully manage/eliminate their IBS-D, starting from th

Hi all. I had IBS pretty much since birth. I was constipated consistently from birth through young adulthood. Then I was constipated off and on until about 2 years ago. I developed diarrhea as a frequent symptom. I isolated lactose as the likely culprit and my doctor encouraged me to eliminate all d

Hi everyone! After 3 years dealing with IBS-D and trying all kinds of treatments, I finally decided to share my story. I’m not fluent in English, so please forgive any mistakes. I just really wanted to share everything I’ve been through — maybe it can help someone feel less alone or give some ideas

I have been struggling with IBS-D for about 3 years. It has varied over time but eventually became a daily episode of liquid BM after first coffee or any food. I had to get up at 5:30 to allow time for it all to be done by 7. Nothing helped. I took Mesalamine and eventually daily Imodium, it only h

(sorry that the post is so long and also for any mistakes English isn't me 1st language) Hi I'm 15 I've been in a flare up, stuck in my house for a year now. The entire year almost non stop I've had diarrhea I'm going to the bathroom 5-8 times in the day and I'm waking up 3-6 times at night, the wo

Hey y’all. I’m new to this group and would really appreciate some advice or suggestions. I’m 25 and Ive recently been diagnosed with UC and Gastritis and for the past 7 months one of the biggest symptoms I have is excessive burping. After eating. Before eating when im hungry. After taking a sip of

Throat is very sensitive and raw from acid I have these coughing fits and sometimes I can’t stop coughing. Please please please help me with recommendations of how to soothe my throat and stop the tickle feeling that makes me want to cough. I know menthol could potentially make it worse so I’m tryi

For context: for pretty much all of last year over 80% of my body was covered in eczema rash. It was so severe I couldn't use the shower and had to either take baths or wash myself in the sink. My scalp was constantly peeling and I was *always* itchy. While my skin would get better in summer, it was

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Hey everyone! I just wanted to provide some sort of update having been on Upadacitinib for just over a month. My eczema is gone and I no longer need to take cold showers and I don't even need to moisturise after showers. My skin looks healthy and clear it is so surreal. This medication is not a ste

Welcome back to this week's newsflash 1. Vedolizumab, a medication used for ulcerative colitis, shows promise in treating chronic pouchitis as well. A new study found it to be effective in reducing ulcer count and inducing mucosal healing. Do you want to know [more](https://www.healio.com/news/gastr

I am interested in participating in a clinical trial. I am leaning towards the 3 mentioned in the title, though I would love to hear about any others that seem promising. I am hoping there will be phase 3 trials in my area some time in the first half of 2018 for ABT-494 and PF-04965842. Phase 3 for

About 80% of my body was covered when I went to the dermatologist, so he sent me to hospital for inpatient treatment for 5 days. I did a paraffin bath -> topical steroid -> wet wrap -> emollient treatment twice a day and everything has cleared up. I've been given a metric tonne of moisturiz

Almost a year ago, after years of worsening Atopic Dermatitis, i said enough is enough, and decided to buy Upadacitinib, a JAK inhibitor originally used for rheumatoid arthritis, after reading about very promising clinical trials for AD. When i posted about it many of you guys were surprised about