Compare PAROXETINE (Paroxetine) and VENLAFAXINE (Venlafaxine) — clinical data, side effects, and patient experiences.
Paroxetine, Paxil · SSRI
How it works
12.1 Mechanism of Action The mechanism of action of paroxetine in the treatment of MDD, SAD, OCD, PD, GAD, and PTSD is unknown, but is presumed to be linked to potentiation of sero...
Approved for
Venlafaxine, Effexor · SNRI
How it works
Pharmacodynamics The mechanism of the antidepressant action of venlafaxine in humans is believed to be associated with its potentiation of neurotransmitter activity in the CNS. Pre...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 25 Reddit discussions
PAROXETINE
17%
positive
12 threads
VENLAFAXINE
62%
positive
13 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for PAROXETINE
Overall Sentiment
Slightly negative
Comparison Threads
0
Avg Post Score
33 upvotes
Most discussed side effects in community
Yes, some individuals will be on them for life, not have issues and good success on them. Some will struggle hard and not be able to get off of them or find one that works well for them. Some will get their bodies destroyed and have the hardest fight of their life to get off these medications. I am
I've read so many sad/bad stories about Paxil/Paroxetine while I was still on it, that I decided I'll write my own once I'm off meds, so that people who are afraid of Paxil after reading all the spooks and scares, would see success stories too. I had major panic attacks and severe anxiety. Anxiety h
How come a psychiatrist prescribes an antidepressant and tells the patient to not look at the side effects? He also assured that there were no effects on sexual function despite the fact that paroxetine is used to treat premature ejaculation in several studies. After deciding to stop paroxetine (due
I just saw a post on instagram and people were saying that brain zaps were genuinely the worst experience of their life, and someone even went to the ER because of it. I’m on day 3 of Paroxetine and I don’t even want to continue (obviously know I can’t just quit now) because of these side effects. I
Hey, looking for a place to vent a little and maybe get some validation. I'm so, so mad and now even more scared as it seems I'm getting no medical help on this. I've stopped Paxil around Christmas. Obviously, I started getting all the fun side effects such as insomnia, nausea and most of all the br
This may seem crazy. But when i was 20ish i was prescribed Deroxat (Paroxetine) for mild depression an social anxiety It worked right from day one, i was numb as wood, that sounds odd but for the first time i didn't have negative feeling (nor good) and that was sooo fucking relaxing, not worrying a
Hi Reddit! I just wanted to say that hope is out there. I'm using a throw-away for obvious reasons. Here is my story. ---------------------------------------------------------------------------------------------------------------------------------------------- I had been sinking into depression wors
Hello everybody, I hope all of you are doing okay. So I went on a trip 5 days ago, while everything was on point, I forgot the most important thing to bring with me, I thought it was already in the luggage so I have not bothered checking twice. I take Paroxetine 40mg, and the withdrawals are mild, n
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
13 Reddit threads analysed for VENLAFAXINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
69 upvotes
Most discussed side effects in community
I just needed to vent about my depression and my issues with society's stance on it somewhere. I thought these were supposed to be the best years of my life? I'm not ugly, and I like to think I'm funny and friendly, so why don't people like me? I'm always alone. Always, always, always. I've spent my
Chronic fatigue. I feel so so tired and weak all the time. Brain fog so bad it is even hard to read and comprehend stuff. Insomnia. I have to take strong sedatives to sleep. I feel like death after waking up. Developed bruxism in my sleep. Noticed it only after it fvcked up all my teeth and they s
Hi all, I unfortunately, went through a tough antidepressant withdrawal from Venlafaxine, and after finding out how common the issue was I decided to get started on creating an application to help. The app is simple and just allows you to keep track of your symptoms as they come, so you can identify
*This is more of a rant than anything. I'm sorry for the formatting. I am on mobile and not really able to think clearly right now*   One month ago, I was put in a psych ward by my parents (I'm still a minor) during what was one of the worst depressive episodes I have ever had. I was physic
I am at the end of my rope right now, and I have nowhere else to go except jump. I wake up every morning wishing it would all stop, and it's my last thought before falling asleep. I am finishing up my PhD this year, but I don't have nearly the job prospects I was expecting. I am in a field as a m
*This is a super long post*, but before I started my AD I was looking for something detailed like this to see people's progressions on their meds. I had a hard time finding much, and this is why I decided to track my own progress and share after 6 weeks. Backstory: 26yr F, have had anxiety and mild
I take Venlafaxine. Just increased from 75 mg to 150 mg. I used to masturbate a lot. Not everyday...but most days. Now I have absolutely zero urge to. I’m talking to a girl now and she says that she’s a “freak” sexually. But I’m basically asexual now because of my meds. So of course.
Hi, Reddit, Over the past month, I have been weaning off of Venlafaxine, I was only on it for 3 months but it has been a debilitating experience that should be taken seriously! After a lot of research, I have noticed many people have been taking these medications for years and the withdrawal symptom
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
PAROXETINE is a SSRI, while VENLAFAXINE belongs to the SNRI class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
PAROXETINE carries 4 FDA warnings. VENLAFAXINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.