Compare PREGABALIN (PREGABALIN) and VENLAFAXINE (Venlafaxine) — clinical data, side effects, and patient experiences.
PREGABALIN, Lyrica, Alzain · Anticonvulsant
How it works
Other agent
Approved for
Venlafaxine, Effexor · SNRI
How it works
Pharmacodynamics The mechanism of the antidepressant action of venlafaxine in humans is believed to be associated with its potentiation of neurotransmitter activity in the CNS. Pre...
Approved for
Estimated frequency (%) based on clinical trial data
Based on 25 Reddit discussions
PREGABALIN
25%
positive
12 threads
VENLAFAXINE
62%
positive
13 threads
% of discussions mentioning each side effect
12 Reddit threads analysed for PREGABALIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
234 upvotes
Most discussed side effects in community
6 years ago I broke my knee playing rugby. I was 33. I had a fair bit of metal put in and lots and lots of rehab. 2 years on crutches and over 4 years of physio. Nothing helped the pain and they removed the metal, which also didn’t help. I had a nerve block injection and was told it may stop the pai
In 2018 I started having daily headaches, it was in my temples, eyebrows/forehead and neck/occipital. I was bedridden for 6 years, unable to work, study, clean my own bedroom or even watching something on TV. I've taken every possible migraine medication: topiramate, emgality, amitriptyline, pregaba
The Italian Society for Rheumatology (SIR) has developed 17 recommendations for the diagnosis and management of fibromyalgia syndrome (FMS), emphasizing a comprehensive, individualized, and evidence-based approach. Below is a summary of these recommendations: 1. Comprehensive Evaluation: FMS manage
I've had to move back home due to the cost of living be so high and my mum has taken my dihydrocodeine from me. She says I take it everyday and am addicted. She says that I should just take paracetamo and be on a pain patch. I'm only taking my dihydrocodeine as prescribed for my slipped discs and p
25F just recently diagnosed so I went to the pharmacy to pick up pregabalin prescribed by my rheumatologist. Of course I hadn’t taken it before so I asked the pharmacist to go over it with me. He asks “what’s it for”? I say “fibromyalgia” then the comments of “wow you’re pretty young for that”. I gu
Title says all. I was recently diagnosed with fibro after testing negative for other autoimmune and muscle diseases. However I seem to have a unique version where I experience 24/7 muscle stiffness and inflammation. Being a little risqué, it feels like I'm tightly wrapped up in BDSM-type rope all ov
I started with 1.5mg and slowly worked my way to 4.5mg, going up 0.5mg at a time. Since the very first dose, I noticed a decrease in pain. With every single dose increase, the pain relief got better and better. When I hit 3.5mg, I had ZERO pain the next day during my 8 hours of work. That’s right -
Just a vent post really. Why is every single medical appointment such a fucking fight every time to advocate for myself and be heard??? Like even with pain management doctors who are supposed to want to help people like me. I literally asked about pregabalin because we haven’t really tried many me
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
13 Reddit threads analysed for VENLAFAXINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
69 upvotes
Most discussed side effects in community
I just needed to vent about my depression and my issues with society's stance on it somewhere. I thought these were supposed to be the best years of my life? I'm not ugly, and I like to think I'm funny and friendly, so why don't people like me? I'm always alone. Always, always, always. I've spent my
Chronic fatigue. I feel so so tired and weak all the time. Brain fog so bad it is even hard to read and comprehend stuff. Insomnia. I have to take strong sedatives to sleep. I feel like death after waking up. Developed bruxism in my sleep. Noticed it only after it fvcked up all my teeth and they s
Hi all, I unfortunately, went through a tough antidepressant withdrawal from Venlafaxine, and after finding out how common the issue was I decided to get started on creating an application to help. The app is simple and just allows you to keep track of your symptoms as they come, so you can identify
*This is more of a rant than anything. I'm sorry for the formatting. I am on mobile and not really able to think clearly right now*   One month ago, I was put in a psych ward by my parents (I'm still a minor) during what was one of the worst depressive episodes I have ever had. I was physic
I am at the end of my rope right now, and I have nowhere else to go except jump. I wake up every morning wishing it would all stop, and it's my last thought before falling asleep. I am finishing up my PhD this year, but I don't have nearly the job prospects I was expecting. I am in a field as a m
*This is a super long post*, but before I started my AD I was looking for something detailed like this to see people's progressions on their meds. I had a hard time finding much, and this is why I decided to track my own progress and share after 6 weeks. Backstory: 26yr F, have had anxiety and mild
I take Venlafaxine. Just increased from 75 mg to 150 mg. I used to masturbate a lot. Not everyday...but most days. Now I have absolutely zero urge to. I’m talking to a girl now and she says that she’s a “freak” sexually. But I’m basically asexual now because of my meds. So of course.
Hi, Reddit, Over the past month, I have been weaning off of Venlafaxine, I was only on it for 3 months but it has been a debilitating experience that should be taken seriously! After a lot of research, I have noticed many people have been taking these medications for years and the withdrawal symptom
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
PREGABALIN is a Anticonvulsant, while VENLAFAXINE belongs to the SNRI class. This means they work through different pharmacological mechanisms, which may influence both efficacy and side effect profiles.
PREGABALIN carries 4 FDA warnings. VENLAFAXINE carries 4 FDA warnings. Patients should discuss all warnings and contraindications with their healthcare provider before starting or switching medications..
This comparison is for informational purposes only. Always consult a qualified healthcare professional before making medication decisions.
Every figure on this comparison links back to its primary source. See data sources and methodology for the full provenance trail.