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Brand names: Allopurinol, Zyloprim
12.1 Mechanism of Action Allopurinol tablets are a structural analogue of the natural purine base, hypoxanthine. Allopurinol acts on purine catabolism, without disrupting the biosynthesis of purines. It reduces the production of uric acid by inhibiting the biochemical reactions immediately preceding its formation. It is an inhibitor of xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and of xanthine to uric acid, the end product of purine metabolism in humans. Allopurinol is metabolized to the corresponding xanthine analogue, oxypurinol (alloxanthine), which also is an inhibitor of xanthine oxidase.
9 documented side effects by frequency
13 Reddit threads analysed for ALLOPURINOL
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Most discussed side effects in community
Age: 59 Weight: 145lbs Complaint: Stroke followed by approximately 30 hours without medical care. He had a previous stroke 2 weeks ago and was transported by ambulance to a hospital. Hospital care is no longer possible. For most of the last 24 hours, he has been unable to move most of his body
Hey guys, I'm finishing my P2 year of pharm school eventually working in independent retail and this question has yet to be addressed: What are the top 10 (or top 5) ABSOLUTE contraindications that are often seen/relevant to retail/commonly missed by physicians? PharmTimes did an [article](http:/
Hello! I went to my doctor about 6 weeks ago due to moderate to severe testicular pain (the right side specifically) and was tested for STDs, STIs or other urinary issues and all came back clear. I was given antibiotics and an ultrasound was ordered. The ultrasound showed a 10mm lesion on my right t
90+ Year old female Patient (family member), non-smoker, and weighs somewhere in the 130-140 range??? (guesstimate), and... anywhere between 5'1" - 5'4" (guesstimate) Med Hx: A-fib (some reason PT was not placed on a long term blood thinning medication and most likely the cause for this incident), G
I am a 61 y.o. male, 5'10", 209 lb, white. I smoke a cigar almost every day outdoors (do not inhale). I have a couple of drinks a week, I do not use other drugs. Also, I do resistance training almost every day and walk about 5 miles per day. So although my weight seems fairly high, I have more t
I was involved in an explosion a few years ago. I was burnt and whatnot and knocked around, but I don't think I ever lost consciousness from it. It was a pretty forceful explosion - it left a small crater in the concrete and knocked people over several metres away. The stuff I was holding in my hand
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7 available comparisons
Dosage Forms
Tablet
Route
Oral