ANACAULASE-BCDB

Other

Brand names: NEXOBRID

Topical

Mechanism of Action

12.1 Mechanism of Action The mixture of enzymes in NEXOBRID dissolves burn wound eschar. The specific components responsible for this effect have not been identified.

Indications

perineum

implants

pacemakers

shunts) or vital structures (e.g.

perineum

implants

Contraindications

• 4 CONTRAINDICATIONS NEXOBRID is contraindicated in patients with [see Warnings and Precautions ( 5.1 )
• Description ( 11 )] : Known hypersensitivity to anacaulase-bcdb
• bromelain
• pineapples
• or to any of the other components. Known hypersensitivity to papayas or papain because of the risk of cross-sensitivity. Known hypersensitivity to anacaulase-bcdb

FDA Warnings

5 WARNINGS AND PRECAUTIONS Hypersensitivity reactions : Serious hypersensitivity reactions, including anaphylaxis, have been reported with postmarketing use of anacaulase-bcdb
Use with caution in patients on anticoagulant therapy or other drugs affecting coagulation, and in patients with low platelet counts and increased risk of bleeding from other causes
1 Hypersensitivity Reactions NEXOBRID-Treated Patients Serious hypersensitivity reactions, including anaphylaxis, have been reported with postmarketing use of NEXOBRID
NEXOBRID is contraindicated in patients with a known hypersensitivity to anacaulase- bcdb, bromelain, pineapples or to any other component of NEXOBRID

Known Side Effects

0 documented side effects by frequency

No structured side effect data available.

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Formulations

Dosage Forms

Tablet

Route

Topical