BETAMETHASONE DIPROPIONATE

Other

Brand names: Betamethasone Dipropionate, Betnovate, Betacap, Diprosone, Celestoderm

Topical

Mechanism of Action

12.1 Mechanism of Action Corticosteroids play a role in cellular signaling, immune function, inflammation, and protein regulation; however, the precise mechanism of action of betamethasone dipropionate cream (augmented) in corticosteroid responsive dermatoses is unknown.

Indications

0.05% is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses in patients 13 years of age and older. ( 1 )

Contraindications

• 4 CONTRAINDICATIONS Betamethasone dipropionate cream (augmented)
• is contraindicated in patients who are hypersensitive to betamethasone dipropionate
• to other corticosteroids
• or to any ingredient in this preparation. Hypersensitivity to any component of this medicine. ( 4 )

FDA Warnings

5 WARNINGS AND PRECAUTIONS Effects on endocrine system: Betamethasone dipropionate cream (augmented) can cause reversible HPA axis suppression with the potential for glucocorticosteroid insufficiency during and after withdrawal of treatment
Risk factor(s) include the use of high-potency topical corticosteroids, use over a large surface area or to areas under occlusion, prolonged use, altered skin barrier, liver failure, and use in pediatric patients
4 ) Ophthalmic Adverse Reactions: Betamethasone dipropionate cream (augmented) may increase the risk of cataracts and glaucoma
2 Ophthalmic Adverse Reactions Use of topical corticosteroids, including betamethasone dipropionate cream (augmented), may increase the risk of posterior subcapsular cataracts and glaucoma

Known Side Effects

11 documented side effects by frequency

Nausea

1-10%

Weight Loss

0.1-1%

Drug Not Working

>10%

Itching

1-10%

Headache

1-10%

Rash

1-10%

Diarrhea

1-10%

Fatigue

1-10%

Shortness of Breath

0.1-1%

General Unwellness

0.1-1%

Fever

0.1-1%

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Formulations

Dosage Forms

Tablet

Route

Topical