BROMFENAC OPHTHALMIC SOLUTION 0.09%

Ophthalmic Agent

Brand names: Bromfenac Ophthalmic Solution 0.09%

Pregnancy: Category COphthalmic

Mechanism of Action

12.1 Mechanism of Action Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) that has anti-inflammatory activity. The mechanism of its action is thought to be due to its ability to block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2. Prostaglandins have been shown in many animal models to be mediators of certain kinds of intraocular inflammation. In studies performed in animal eyes, prostaglandins have been shown to produce disruption of the blood-aqueous humor barrier, vasodilation, increased vascular permeability, leukocytosis, and increased intraocular pressure.

Indications

See full prescribing information

Contraindications

• 4 CONTRAINDICATIONS None.

FDA Warnings

5 WARNINGS AND PRECAUTIONS Sulfite Allergic Reactions ( 5
, dry eye syndrome), rheumatoid arthritis, or repeat ocular surgeries within a short period of time may be at increased risk for corneal adverse events which may become sight threatening
Post-marketing experience with topical NSAIDs also suggests that use more than 24 hours prior to surgery or use beyond 14 days post surgery may increase patient risk for the occurrence and severity of corneal adverse events

Known Side Effects

6 documented side effects by frequency

Blurred Vision

1-10%

Drug Not Working

1-10%

Fatigue

1-10%

Dizziness

0.1-1%

Headache

0.1-1%

Nausea

0.1-1%

Community Discussions

1 Reddit threads analysed for BROMFENAC OPHTHALMIC SOLUTION 0.09%

Overall Sentiment

Mixed

Comparison Threads

Avg Post Score

132 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

Cocaine hydrochloride is blue

r/pharmacy132291mo ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Compare With

2 available comparisons

Formulations

Dosage Forms

Tablet

Route

Ophthalmic