BUDESONIDE

Corticosteroid

Brand names: Budesonide, Pulmicort, Rhinocort, Symbicort, Entocort, Budelin

Oral

Mechanism of Action

12.1 Mechanism of Action Budesonide is an anti-inflammatory corticosteroid and has a high glucocorticoid effect and a weak mineralocorticoid effect, and the affinity of budesonide to glucocorticoid receptors, which reflects the intrinsic potency of the drug, is about 200-fold that of cortisol and 15-fold that of prednisolone.

Indications

1 INDICATIONS AND USAGE Budesonide delayed-release capsules are a corticosteroid indicated for: Treatment of mild to moderate active Crohn’s disease involving the ileum and/or the ascending colon

Contraindications

• including anaphylaxis have occurred [see Adverse Reactions (6.2) ] . Hypersensitivity to budesonide or any of the ingredients in budesonide delayed-release capsules. ( 4 )

FDA Warnings

5 WARNINGS AND PRECAUTIONS Hypercorticism and Adrenal Axis Suppression: May occur with treatment; monitor for signs and symptoms; pediatrics and patients with hepatic impairment may be at increased risk
2 ) Immunosuppression and Increased Risk of Infection: Increased risk of viral, bacterial, fungal, protozoal and helminthic infections, including potentially fatal varicella and measles infection
Patients with moderate to severe hepatic impairment (Child-Pugh Class B and C respectively) could be at an increased risk of hypercorticism and adrenal axis suppression due to an increased systemic exposure of oral budesonide
3 Immunosuppression and Increased Risk of Infection Corticosteroids, including budesonide, suppress the immune system and increase the risk of infection with any pathogen, including viral, bacterial, fungal, protozoan, or helminthic pathogens

Known Side Effects

8 documented side effects by frequency

Shortness of Breath

>10%

Drug Not Working

1-10%

Cough

1-10%

Fatigue

1-10%

Headache

1-10%

General Unwellness

0.1-1%

Nausea

0.1-1%

Diarrhea

0.1-1%

Community Discussions

5 Reddit threads analysed for BUDESONIDE

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

150 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

Old school swag at my pharmacy!

Ketek & Vioxx?!💀

r/pharmacy350702y ago

An interaction that I had today

I don't post often at all so forgive if the story doesn't feel fully fleshed out or written with a ton of experience. Let me know in comments some constructive criticism to improve future posts. I'm planning on posting more stories from work like this. This happened right after I started my shift th

r/pharmacy267796y ago

The shit PBMs get away with and most don’t even know they exist!

I caught my PBM doing some really shitty things this year... last year it was a suspicion, this year I caught them stealing from the cookie jar. When I shared what happened with my family and friends the majority had never even heard of them! So I’m going to share here where people get it. I hit my

r/pharmacy99396y ago

window policy about leaning halfway out to hand over a large RX, unable to hear one another on cold windy days, etc

In the last couple weeks I've had a) an over inflated DB who grumpled at me at the window about how he can’t hear me on a windy day, being ID’ed for a controlled substance, and came in to complain about ‘the worst ComeVisitSatan experience he’s ever had and b) another entitled dude who was parked wa

r/pharmacy23106y ago

Budesonide Suspension?

So, two days ago on my shift, a doctor sent in a prescription for a patient for Budesonide nebulizer solution. In his notes, it stated for the pharmacist to watch a video on how to turn this solution (in the individual vials) into a suspension, and have the patient swallow it four times a day. We do

r/pharmacy11125y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Compare With

23 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral