CARBIDOPA LEVODOPA

Parkinson's Agent

Brand names: Dhivy

Oral

Mechanism of Action

Other agent

Indications

1 INDICATIONS AND USAGE DHIVY is indicated for the treatment of Parkinson’s disease

post-encephalitic parkinsonism

and symptomatic parkinsonism that may follow carbon monoxide intoxication or manganese intoxication ( 1 )

Contraindications

• 4 CONTRAINDICATIONS DHIVY is contraindicated in patients Currently taking a nonselective monoamine oxidase (MAO) inhibitor (e.g.
• phenelzine
• linezolid

FDA Warnings

5 WARNINGS AND PRECAUTIONS May cause falling asleep during activities of daily living ( 5
1 ) Avoid sudden discontinuation or rapid dose reduction to reduce the risk of withdrawal-emergent hyperpyrexia and confusion ( 5
1 Falling Asleep During Activities of Daily Living and Somnolence Patients taking carbidopa/levodopa alone or with other dopaminergic drugs have reported suddenly falling asleep without prior warning of sleepiness while engaged in activities of daily living, including the operation of motor vehicles which have resulted in accidents
Although many patients reported somnolence while on dopaminergic medications, some perceived that they had no warning signs (sleep attack), such as excessive drowsiness, and believed that they were alert immediately prior to the event

Known Side Effects

9 documented side effects by frequency

Falls

>10%

Drug Not Working

>10%

Tremor

1-10%

Dizziness

1-10%

Nausea

1-10%

Fatigue

1-10%

Drowsiness

0.1-1%

Weakness

0.1-1%

UTI

0.1-1%

Community Discussions

1 Reddit threads analysed for CARBIDOPA LEVODOPA

Overall Sentiment

Mixed

Comparison Threads

Avg Post Score

2 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

parkinsonism

Age 78. Female. Wisconsin My mom has some symptoms related to parkinsons, noticeably a hand tremor and a lip tremor. One doctor labeled it has an essential tremor. A neurologist labeled it as "parkinsonism". She was prescribed carbidopa and levodopa. These meds appear to be routine for parkinsons. I

r/AskDocs243y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Compare With

10 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral