CLOMIPRAMINE HYDROCHLORIDE

Tricyclic Antidepressant

Brand names: CLOMIPRAMINE HYDROCHLORIDE

Oral

Mechanism of Action

Other agent

Indications

INDICATIONS AND USAGE Clomipramine hydrochloride capsules

USP is indicated for the treatment of obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD). The obsessions or compulsions must cause marked distress

be time-consuming

or significantly interfere with social or occupational functioning

in order to meet the DSM-III-R (circa 1989) diagnosis of OCD. Obsessions are recurrent

persistent ideas

Contraindications

• CONTRAINDICATIONS Clomipramine hydrochloride capsules
• USP are contraindicated in patients with a history of hypersensitivity to clomipramine hydrochloride capsules
• USP or other tricyclic antidepressants. Monoamine Oxidase Inhibitors (MAOIs) The use of MAOIs intended to treat psychiatric disorders with clomipramine hydrochloride capsules
• USP or within 14 days of stopping treatment with clomipramine hydrochloride capsules
• USP are contraindicated because of an increased risk of serotonin syndrome. The use of clomipramine hydrochloride capsules

FDA Warnings

Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of major depressive disorder (MDD) and other psychiatric disorders
Anyone considering the use of clomipramine hydrochloride or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need
Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older
Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide

Known Side Effects

9 documented side effects by frequency

Drowsiness

1-10%

Falls

1-10%

Tremor

1-10%

Nausea

1-10%

Drug Not Working

1-10%

Anxiety

1-10%

Depression

1-10%

General Unwellness

1-10%

Rapid Heart Rate

1-10%

Community Discussions

2 Reddit threads analysed for CLOMIPRAMINE HYDROCHLORIDE

Overall Sentiment

Mixed

Comparison Threads

Avg Post Score

4 upvotes

Most discussed side effects in community

Headache (1)

Muscle Pain (1)

Anxiety (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

Reoccuring tear(wound?) at the same smallest tow toes in feet

first sorry for bad English it is my 4th language. I M19, smoker frequency of 3 cigs per week for 3 months now, 168cm 88kg, history of igg4 autoimmune pancreatitis and liver/small intestine damage due to same condition, been on immunosuppresors for 8 months, and had previously had been on high dose

r/AskDocs651mo ago

Vision getting darker suddenly, then back to normal

Hi, I'm 23,ftm, 1.73 m tall, 130 kg, Caucasian, non smoker, rarely use alcohol or weed, never anything stronger unless prescribed by a doctor. Diagnosed with OCD, PTSD, major depressive episodes, anxiety. Also diagnosed with scheuermann's disease, kyphosis, scoliosis, migraines, epilepsy (is new and

r/AskDocs111y ago

Headache

Muscle Pain

Anxiety

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Compare With

12 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral