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Brand names: Darifenacin, Enablex
12.1 Mechanism of Action Darifenacin is a competitive muscarinic receptor antagonist. Muscarinic receptors play a role in cholinergically mediated functions, including contractions of the urinary bladder smooth muscle. In vitro studies using human recombinant muscarinic receptor subtypes show that darifenacin has greater affinity for the M 3 receptor than for the other known muscarinic receptors (9- and 12-fold greater affinity for M 3 compared to M 1 and M 5 , respectively, and 59-fold greater affinity for M 3 compared to both M 2 and M 4 ). M 3 receptors are involved in contraction of human bladder.
Contraindications
2 documented side effects by frequency
5 Reddit threads analysed for DARIFENACIN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
10 upvotes
Most discussed side effects in community
Hello, This is my first ever reddit post (although I also posted it on the IC subreddit...) I was so inspired by everyone on this thread and I feel I would love answers/ solutions/ thoughts from people here. My symptoms are changing a bit, but the basics are that I just need to pee a lot. all the
Hi everyone. First, I want to apologize if my English isn’t perfect. It’s not my first language and I used a translator, but I’ll do my best to explain. I’m posting here because I’ve been dealing with something very frustrating for a little over a month and I’m starting to feel really exhausted and
Hello, This is my first ever reddit post, I was so inspired by everyone on this thread and I feel I would love answers/ solutions/ thoughts from people here. My symptoms are changing a bit, but the basics are that I just need to pee a lot. all the time. Like, as soon as my bladder is 'empty' I need
Hi everyone. First, I want to apologize if my English isn’t perfect. It’s not my first language and I used a translator, but I’ll do my best to explain. I’m posting here because I’ve been dealing with something very frustrating for a little over a month and I’m starting to feel really exhausted and
Context first, the list of meds I'm inquiring about are under that. So tomorrow I go for my second round, where I meet a new urologist. Last month I went to one, an older man and he ordered a cystoscopy., but when I told him that I feel I need general anesthesia, he laughed and told me I wouldn't
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
4 available comparisons
Dosage Forms
Tablet
Route
Oral