DESMOPRESSIN ACETATE ORAL SOLUTION

Other

Brand names: DESMODA

Oral

Mechanism of Action

12.1 Mechanism of Action Desmopressin acetate’s primary pharmacodynamic action involves its binding to vasopressin 2 (V2) receptors. V2 receptors are primarily located in the distal convoluted tubule and collecting ducts of the nephron in the kidneys. These receptors play a crucial role in regulating water reabsorption and urine concentration. By influencing the permeability of the renal tubules, V2 receptors help maintain the body’s water balance and overall homeostasis.

Indications

See full prescribing information

FDA Warnings

5 WARNINGS AND PRECAUTIONS 5
Unless properly diagnosed and treated hyponatremia can be fatal
In order to decrease the risk of water intoxication with hyponatremia, fluid restriction is recommended
Careful fluid intake is particularly important in pediatric and geriatric patients because these patients are at greater risk of developing hyponatremia [see Use in Specific Populations (8

Known Side Effects

12 documented side effects by frequency

Drug Not Working

>10%

Headache

1-10%

Nausea

1-10%

Fatigue

1-10%

Vomiting

1-10%

Dizziness

1-10%

Diarrhea

1-10%

Weakness

0.1-1%

General Unwellness

0.1-1%

Fever

0.1-1%

Shortness of Breath

0.1-1%

Falls

0.1-1%

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Formulations

Dosage Forms

Tablet

Route

Oral