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Brand names: Dorzolamide Hydrochloride, Trusopt
12.1 Mechanism of Action Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II), found primarily in red blood cells (RBCs), but also in other tissues. Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure (IOP). Dorzolamide hydrochloride ophthalmic solution contains dorzolamide hydrochloride, an inhibitor of human carbonic anhydrase II. Following topical ocular administration, dorzolamide hydrochloride ophthalmic solution reduces elevated intraocular pressure. Elevated intraocular pressure is a major risk factor i
Contraindications
5 documented side effects by frequency
8 Reddit threads analysed for DORZOLAMIDE
Overall Sentiment
Mixed
Comparison Threads
1
Avg Post Score
26 upvotes
Most discussed side effects in community
Threads directly comparing DORZOLAMIDE to other medications
I've been taking Rocklatan for about three months now and the discomfort is really getting to me. (And the stares I get for my "stoner" eyes, even after taking Lumify.) I had only tried Latanoprost and Vyzulta before the Rocklatan but they didn't do much to relieve my pressures, which had been as hi
I work at the corner of happy and healthy in an area that's a bunch of small towns. There's several stores in the area that are within 30ish minutes of each other, and I live in a place that's between several of them. As such, there's multiple stores that are within 10-20 minutes of my home that ar
Yara had her right eye removal today, she did well. I didn’t expect her to look so rough it was kind of jarring. Since she has primary glaucoma they have her on eye drops for her remaining eye. They want me to give her dorzolamide/timolol 2x a day and prednisolone acetate 1x a day in her left eye AN
My baby Kai woke up today with a very cloudy eye that he refused to open. I rushed him to the emergency vet who transferred him to another emergency vet and I was told he likely has anterior lens luxation. His pressure was 76 at one point and dropped to 45 the last we checked after administering dor
Hello, My daughter was diagnosed with JIA and Uveitis, you can find my original post [here](https://www.reddit.com/r/rheumatoid/comments/93g82y/us_5_years_old_with_jia_xpost_from_ruveitis/). She had only one join swollen and after just 2/3 weeks taking naproxen twice a day the discomfort went away.
Hello everyone, I’m 28/M. About 7 months ago, I was told I have pigment dispersion syndrome. At that time, a visual field test and an OCT were performed. My IOP back then was around 25-27 mmHg in both eyes. Stupid me didn’t realize how serious this was at the time and probably went around like that
Can anyone who has had their cat go through a double enucleation (eye removal) share their experience? I have a 15 year old diabetic cat who lost his vision almost a year ago. He was diagnosed with glaucoma and put on Dorzolamide to try to keep his eye pressure under control. During his latest rech
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14 available comparisons
Dosage Forms
Tablet
Route
Ophthalmic