DOXYLAMINE SUCCINATE AND PYRIDOXINE HYDROCHLORIDE

Electrolyte / Mineral

Brand names: Doxylamine succinate and Pyridoxine hydrochloride

Oral

12.1 Mechanism of Action The mechanism of action of doxylamine succinate and pyridoxine hydrochloride is unknown.

an antihistamine

and pyridoxine hydrochloride

a Vitamin B 6 analog

indicated for the treatment of nausea and vomiting of pregnancy in women who do not respond to conservative management. ( 1 )

Contraindications

• other ethanolamine derivative antihistamines
• other ethanolamine derivative antihistamines
• pyridoxine hydrochloride or any inactive ingredient in the formulation. ( 4 ) Monoamine oxidase (MAO) inhibitors. ( 4
• 7 )

5 WARNINGS AND PRECAUTIONS Activities requiring mental alertness: Avoid engaging in activities requiring complete mental alertness, such as driving or operating heavy machinery, while using doxylamine succinate and pyridoxine hydrochloride until cleared to do so by a healthcare provider

11 documented side effects by frequency

Drug Not Working

>10%

Drowsiness

>10%

Fatigue

1-10%

Nausea

1-10%

Dizziness

1-10%

Insomnia

1-10%

Headache

1-10%

Vomiting

0.1-1%

Diarrhea

0.1-1%

Shortness of Breath

0.1-1%

Cough

0.1-1%

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Dosage Forms

Tablet

Route

Oral