DROSPIRENONE

Other

Brand names: drospirenone

Oral

12.1 MECHANISM OF ACTION COCs lower the risk of becoming pregnant primarily by suppressing ovulation.

1 INDICATIONS AND USAGE Drospirenone

ethinyl estradiol and levomefolate calcium tablet and levomefolate calcium tablet is a combination of drospirenone

a progestin and ethinyl estradiol

an estrogen containing a folate

anxiety or tension

affective lability

Contraindications

• 4 CONTRAINDICATIONS Drospirenone
• if over age 35 [see Boxed Warning and Warnings And Precautions ( 5.1 )] Have deep vein thrombosis or pulmonary embolism
• subacute bacterial endocarditis with valvular disease
• or history of
• breast cancer

5 WARNINGS AND PRECAUTIONS Vascular risks : Stop drospirenone, ethinyl estradiol and levomefolate calcium tablets and levomefolate calcium tablets if a thrombotic event occurs
1 ) COCs containing DRSP may be associated with a higher risk of venous thromboembolism (VTE) than COCs containing levonorgestrel or some other progestins
Before initiating drospirenone, ethinyl estradiol and levomefolate calcium tablets and levomefolate calcium tablets in a new COC user or a woman who is switching from a contraceptive that does not contain DRSP, consider the risks and benefits of a DRSP-containing COC in light of her risk of a VTE
03 mg ethinyl estradiol (that is, Yasmin ® ), DRSP-containing COCs may be associated with a higher risk of venous thromboembolism (VTE) than COCs containing the progestin levonorgestrel or some other progestins

5 documented side effects by frequency

Anxiety

1-10%

Nausea

0.1-1%

Abdominal Pain

0.1-1%

Shortness of Breath

0.1-1%

Vomiting

0.1-1%

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Dosage Forms

Tablet

Route

Oral