ERTAPENEM SODIUM

Electrolyte / Mineral

Brand names: Ertapenem

Intramuscular, Intravenous

12.1 Mechanism of Action Ertapenem sodium is a carbapenem antibiotic [see Clinical Pharmacology ( 12.4 )].

Clostridium clostridioforme

Eubacterium lentum

Peptostreptococcus species

Bacteroides fragilis

Bacteroides distasonis

Bacteroides ovatus

Contraindications

• ertapenem for injection administered intramuscularly is contraindicated in patients with a known hypersensitivity to local anesthetics of the amide type. ( 4 )

5 WARNINGS AND PRECAUTIONS Serious hypersensitivity (anaphylactic) reactions have been reported in patients receiving β-lactams
2 ) Co-administration of ertapenem for injection with valproic acid or divalproex sodium reduces the serum concentration of valproic acid potentially increasing the risk of breakthrough seizures
3 ) Clostridioides difficile -associated diarrhea (ranging from mild diarrhea to fatal colitis): Evaluate if diarrhea occurs
1 Hypersensitivity Reactions Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients receiving therapy with beta-lactams

7 documented side effects by frequency

Drug Not Working

>10%

Fever

1-10%

Nausea

1-10%

Weight Loss

0.1-1%

General Unwellness

0.1-1%

Abdominal Pain

0.1-1%

Headache

0.1-1%

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Dosage Forms

Tablet

Route

Intramuscular, Intravenous