ERYTHROMYCIN LACTOBIONATE

Macrolide Antibiotic

Brand names: Erythromycin Lactobionate

Intravenous

Mechanism of Action

Mechanism of Action Erythromycin acts by inhibition of protein synthesis by binding 50 S ribosomal subunits of susceptible organisms. It does not affect nucleic acid synthesis.

Indications

INDICATIONS AND USAGE Erythromycin lactobionate for injection

Streptococcus pneumoniae (Diplococcus pneumoniae)

Haemophilus influenzae (when used concomitantly with adequate doses of sulfonamides

USP

followed by erythromycin stearate or erythromycin base orally

as an alternative drug in treatment of acute pelvic inflammatory disease caused by N. gonorrhoeae in female patients with a history of sensitivity to penicillin. Before treatment of gonorrhea

Contraindications

• CONTRAINDICATIONS Erythromycin is contraindicated in patients with known hypersensitivity to this antibiotic. Erythromycin is contraindicated in patients taking terfenadine or astemizole
• cisapride
• pimozide
• ergotamine
• due to the increased risk of myopathy

FDA Warnings

WARNINGS Hepatotoxicity There have been reports of hepatic dysfunction, with or without jaundice occurring in patients receiving oral erythromycin products
Clostridium difficile -Associated Diarrhea Clostridium difficile -associated diarrhea (CDAD) has been reported with the use of nearly all antibacterial agents, including erythromycin, and may range in severity from mild diarrhea to fatal colitis
Susceptibility to the development of torsades de pointes arrhythmias, a rare but serious cardiac condition, is related to electrolyte imbalance, hepatic dysfunction, myocardial ischemia, left ventricular dysfunction, idiopathic Q-T prolongation, and concurrent antiarrhythmic therapy
Since erythromycin may be used in the treatment of conditions in infants which are associated with significant mortality or morbidity (such as pertussis or chlamydia), the benefit of erythromycin therapy needs to be weighed against the potential risk of developing IHPS

Known Side Effects

11 documented side effects by frequency

Nausea

1-10%

Vomiting

1-10%

Diarrhea

1-10%

Drug Not Working

1-10%

Shortness of Breath

1-10%

Fatigue

1-10%

Rash

1-10%

Headache

1-10%

Dizziness

0.1-1%

Fever

0.1-1%

General Unwellness

0.1-1%

Community Discussions

1 Reddit threads analysed for ERYTHROMYCIN LACTOBIONATE

Overall Sentiment

Positive

Comparison Threads

Avg Post Score

553 upvotes

Most discussed side effects in community

Itching (1)

Patient Experiences (r/pharmacy, r/AskDocs & more)

Actives: An AB Intro Guide and FAQ.

**What are they?** -- "Actives" are the common term for the group of power players in skincare with ingredients that have direct, active results on the skin, and have serious science backing it up. These include acids like AHAs and BHAs, and antioxidants like Vitamin C and Vitamin A (retinol and tr

r/AsianBeauty553709y ago

Itching

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Compare With

7 available comparisons

Formulations

Dosage Forms

Tablet

Route

Intravenous