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Brand names: Felodipine, Plendil
Mechanism of Action Felodipine is a member of the dihydropyridine class of calcium channel antagonists (calcium channel blockers). It reversibly competes with nitrendipine and/or other calcium channel blockers for dihydropyridine binding sites, blocks voltage-dependent Ca ++ currents in vascular smooth muscle and cultured rabbit atrial cells, and blocks potassium-induced contracture of the rat portal vein. In vitro studies show that the effects of felodipine on contractile processes are selective, with greater effects on vascular smooth muscle than cardiac muscle. Negative inotropic effects can be detected in vitro , but such effects have not been seen in intact animals. The effect of felodipine on blood pressure is principally a consequence of a dose-related decrease of peripheral vascular resistance in man, with a modest reflex increase in heart rate (see Cardiovascular Effects ). With the exception of a mild diuretic effect seen in several animal species and man, the effects of felo
Contraindications
13 documented side effects by frequency
8 Reddit threads analysed for FELODIPINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
4 upvotes
Most discussed side effects in community
As title really. Cannot see the option to export as anything other than PDF https://preview.redd.it/q72q0o04afpa1.png?width=2570&format=png&auto=webp&s=310ea629490713aa74316d08dbf285908d52b1bb
I will be needing additional / change in meds as BP remains stubbornly at 160/100 range. Speaking to my GP on Tuesday re next steps. Currently on Ramipiril 10 mg & Indapamide modified release (highest dose). I am 38 F. Post partum hypertension coming to 3 years now. It was in control for 15 mon
Long post ahead! Apologies in advance 🙏 Since I watched Joe Rogan’s podcast (the ep featuring David Sinclair of course 😬) I went down a rabbit hole of research .. anything I could find really (and reading a lot of people’s experiences on here) however I got SO (adhd) overwhelmed by brands, combin
Pharmacological drugs of metabolic and cytoprotective action applied to correction of a functional condition of a myocardium designate the term "cardioprotectors" which appeared in the nineties 20th century when ideas of the most important role of biochemical changes in a pathogenesis of coronar
Long post ahead! Apologies in advance 🙏 Since I watched Joe Rogan’s podcast (the ep featuring David Sinclair of course 😬) I went down a rabbit hole of research .. anything I could find really (and reading a lot of people’s experiences on here) however I got SO (adhd) overwhelmed by brands, combina
age 63yo approximate height & weight 5'4 138 lbs gender Female medications you take hydrochlorothiazide 12.5 mg bid, losartan 50mg smoking status nonsmoker previous and current medical issues hypertension, new onset near syncope duration and location of complaint acute, started today Mom is a 5'
I am a 29-year-old Male Caucasian, who recently started taking Ramipril/ Felodipin (Triapin Mite is the name of the medicine) 5mg once a day. I always had a slightly increased heart rate but since I started taking this drug I catch myself way too often sitting on the computer working, and my Galaxy
Anyone have any experience with Felodipine? I’m start this new course tonight!
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4 available comparisons
Dosage Forms
Tablet
Route
Oral