FLUVASTATIN SODIUM

Electrolyte / Mineral

Brand names: Fluvastatin Sodium

Oral

Mechanism of Action

12.1 Mechanism of Action Fluvastatin is a competitive inhibitor of HMG-CoA reductase, the rate limiting enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) to mevalonate, a precursor of cholesterol.

Indications

See full prescribing information

Contraindications

• including anaphylaxis
• angioedema

FDA Warnings

5 WARNINGS AND PRECAUTIONS Myopathy and Rhabdomyolysis: Risk factors include age 65 years or greater, uncontrolled hypothyroidism, renal impairment, and concomitant use with certain other drugs
Temporarily discontinue fluvastatin in patients experiencing an acute or serious condition at high risk of developing renal failure secondary to rhabdomyolysis
Inform patients of the risk of myopathy and rhabdomyolysis when starting or increasing fluvastatin dosage
Rare reports of fatal and non-fatal hepatic failure have occurred

Known Side Effects

15 documented side effects by frequency

Muscle Pain

>10%

Dizziness

1-10%

Nausea

1-10%

Diarrhea

1-10%

Shortness of Breath

1-10%

Fatigue

1-10%

Weakness

1-10%

Headache

1-10%

Falls

1-10%

Joint Pain

1-10%

Vomiting

1-10%

Fever

1-10%

Itching

1-10%

General Unwellness

1-10%

Abdominal Pain

0.1-1%

Community Discussions

No community discussions found for FLUVASTATIN SODIUM yet.

Compare With

0 available comparisons

No comparisons yet.

Formulations

Dosage Forms

Tablet

Route

Oral