IOHEXOL

Diagnostic Agent

Brand names: Omnipaque

Intravenous

Mechanism of Action

12.1 Mechanism of Action The iodine atoms in iohexol provide attenuation of X-rays in direct proportion to the concentration of iohexol. Since concentration changes over time, iohexol provides time-dependent image contrast which may assist in visualizing body structures.

Indications

1 INDICATIONS AND USAGE OMNIPAQUE is a radiographic contrast agent indicated for intrathecal

intra-arterial

intravenous

oral

rectal

intraarticular

Contraindications

• 4 CONTRAINDICATIONS OMNIPAQUE for hysterosalpingography is contraindicated during pregnancy or suspected pregnancy
• menstruation or when menstruation is imminent
• within 6 months after termination of pregnancy
• within 30 days after conization or curettage
• when signs of infection are present in any portion of the genital tract including the external genitalia

FDA Warnings

5 WARNINGS AND PRECAUTIONS Hypersensitivity Reactions: Life-threatening or fatal reactions can occur
Minimize dose and maintain adequate hydration to minimize risk
5 ) Thyroid Dysfunction in Pediatric Patients 0 to 3 Years of Age: Individualize thyroid function monitoring based on risk factors such as prematurity
1 Risks Associated with Intrathecal Administration of OMNIPAQUE Injection 140 mg Iodine/mL and 350 mg Iodine/mL Use only the iodine concentrations and presentations recommended for intrathecal procedures [see Dosage and Administration (2

Known Side Effects

8 documented side effects by frequency

Itching

>10%

Shortness of Breath

>10%

Nausea

1-10%

Vomiting

1-10%

Rash

1-10%

Cough

0.1-1%

Low Blood Pressure

0.1-1%

Fever

0.1-1%

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Compare With

11 available comparisons

Formulations

Dosage Forms

Tablet

Route

Intravenous