KIT FOR THE PREPARATION OF TECHNETIUM TC 99M PENTETATE

Other

Brand names: Kit for the Preparation of Technetium Tc 99m Pentetate

Intravenous, Respiratory (inhalation)

Mechanism of Action

12.1 Mechanism of Action Intravenous Administration Following intravenous administration for brain and renal imaging, Technetium Tc 99m pentetate is distributed in the vascular compartment. It is cleared by the kidneys, which results in the ability to image the kidney. Aerosolized Inhalation Administration Following inhalation of the aerosol, Technetium Tc 99m pentetate deposits on the epithelium of ventilated alveoli.

Indications

1 INDICATIONS AND USAGE Kit for the Preparation of Technetium Tc 99m Pentetate Injection

after radiolabeling with Technetium Tc 99m

assessment of renal perfusion

FDA Warnings

5 WARNINGS AND PRECAUTIONS Hypersensitivity reactions: Hypersensitivity reactions, including anaphylaxis, have been reported during post-approval diagnostic use of Technetium Tc 99m pentetate injection
Image interpretation risks in lung ventilation studies: If proximal airway deposition is observed, consider additional diagnostic options ( 5
Radiation exposure risk: Technetium Tc 99m pentetate contributes to a patient’s overall long-term radiation exposure ( 2
2 Image Interpretation Risks in Lung Ventilation Studies In patients with obstructive pulmonary disease there may be deposition of particles in the proximal airways influencing image quality and interfering with diagnostic interpretation, therefore to ensure diagnostic quality, careful use of the nebulizer to assure optimal particle delivery is essential

Known Side Effects

11 documented side effects by frequency

Drug Not Working

>10%

Fatigue

1-10%

Nausea

1-10%

Itching

1-10%

Vomiting

1-10%

Headache

1-10%

Diarrhea

1-10%

Falls

1-10%

Dizziness

1-10%

Rash

1-10%

Shortness of Breath

1-10%

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Formulations

Dosage Forms

Tablet

Route

Intravenous, Respiratory (inhalation)