MEDROXYPROGESTERONE ACETATE

Hormone

Brand names: MEDROXYPROGESTERONE ACETATE

Intramuscular

Mechanism of Action

12.1 Mechanism of Action Medroxyprogesterone acetate (MPA) injectable suspension, inhibits the secretion of gonadotropins which primarily prevents follicular maturation and ovulation and causes thickening of cervical mucus. These actions contribute to its contraceptive effect.

Indications

longer than 2 years) birth control method unless other options are considered inadequate. (1

5.1)

Contraindications

• or current or past history of thromboembolic disorders
• or current or past history of thromboembolic disorders

FDA Warnings

5 WARNINGS AND PRECAUTIONS Thromboembolic Disorders: Discontinue medroxyprogesterone acetate injectable suspension in patients who develop thrombosis
2 ) Cancer Risks: Monitor women with a strong family history of breast cancer carefully
It is unknown if use of medroxyprogesterone acetate injectable suspension by younger women will reduce peak bone mass and increase the risk for osteoporotic fracture in later life
Other birth control methods should be considered in the risk/benefit analysis for the use of medroxyprogesterone acetate injectable suspension in women with osteoporosis risk factors

Known Side Effects

9 documented side effects by frequency

Drug Not Working

0.1-1%

Nausea

0.1-1%

Headache

0.1-1%

Depression

0.1-1%

Fatigue

0.1-1%

Anxiety

0.1-1%

Weight Gain

0.1-1%

Dizziness

0.1-1%

Shortness of Breath

0.1-1%

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Compare With

15 available comparisons

Formulations

Dosage Forms

Tablet

Route

Intramuscular