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Brand names: Memantine hydrochloride, Namenda
12.1 Mechanism of Action Persistent activation of central nervous system N-methyl-D-aspartate (NMDA) receptors by the excitatory amino acid glutamate has been hypothesized to contribute to the symptomatology of Alzheimer’s disease. Memantine is postulated to exert its therapeutic effect through its action as a low to moderate affinity uncompetitive (open-channel) NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. There is no evidence that memantine prevents or slows neurodegeneration in patients with Alzheimer’s disease.
10 documented side effects by frequency
15 Reddit threads analysed for MEMANTINE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
91 upvotes
Most discussed side effects in community
Story time, I moved across the country to be with my fiance. I went to the hospital for a really killer migraine, and everyone at the ER mentioned this neurologists name, one person mentioned it I didn't think much of it, but when nurse after nurse and then the doctor even mentioned his name I was l
So I have a history of migraines, obviously. Usually they'd be 1-3 times per month randomly. Or if I encounter a trigger of some sort. Imitrex usually takes care of them, though a few times I've had to go to ER/Urgent Care for the migraine cocktail. Within the last month or so though I've had a h
I was fired from my job last week for discriminatory reasons. I'm not sure if I should bother taking legal action. For fuck's sake, I am physically and mentally exhausted. This morning I woke up with visual aura and almost tripped while getting out of bed due to warped depth perception. (I was tryin
My neurologist recently suggested I see another headache specialist at a larger clinic to get a different perspective on my headaches, as they were refractive to almost everything he tried, and have been for a few years. My regimen with him is Botox, which had me down to about 8 headaches a month,
My mom is 70 and I’m 31 and an only child. Everyday I see my mom deteriorating and I want to just cry because of how scary it is and how lonely I feel. I don’t have anyone else to share this experience with of caretaking and it’s so isolating. My mom is diagnosed with Alzheimer’s but recently it’
I compiled Full list of migraine medication that I found. If you can add something to the list - i would be thanksfull !!! Please,never use any of them before consultation with doctor, even Nsaids/pain relievers that look harmless cause big headaches if you use Them more than 8-10 times a month **In
Guys I thought I was losing my mind. I’m 52 and I can’t follow a conversation, I have trouble remembering what I’m watching if a commercial comes on. It’s been terrifying. Thank God for Reddit. My migraines have been at least 3x a week for more than 20 years and NEVER did my neurologist tell me ALL
My mom, 90, early-going-into-moderate Alzheimers, used to ask me almost daily about a "cure," or when she's getting this or that new drug she's read about (she graduated off Aricept, had bad side effects on Memantine, and was denied Lequembi for being too risky). Today, she damn nearly cornered me:
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
10 available comparisons
Dosage Forms
Tablet
Route
Oral