How does METFORMIN ER 500 MG work?

METFORMIN ER 500 MG works through the following mechanism: Other agent.

What are the most common side effects of METFORMIN ER 500 MG?

Reported side effects vary by individual. The side-effects section on this page lists the events most frequently reported to FDA FAERS for METFORMIN ER 500 MG. FAERS is voluntary reporting, so it reflects what was reported, not absolute incidence.

Is METFORMIN ER 500 MG the same as Metformin?

Metformin is a brand name for METFORMIN ER 500 MG. They share the same active ingredient and FDA-approved indications. Biosimilars and authorised generics may differ in inactive ingredients such as buffers or preservatives.

METFORMIN ER 500 MG

Q: What is METFORMIN ER 500 MG used for?

METFORMIN ER 500 MG (brand name Metformin) is a Biguanide indicated for INDICATIONS & USAGE Metformin hydrochloride extended-release tablets, USP are indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus..

Biguanide

Brand names: Metformin, Jentadueto XR

Pregnancy: Category BOral

Mechanism of Action

Other agent

Indications

INDICATIONS & USAGE Metformin hydrochloride extended-release tablets

USP are indicated as an adjunct to diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus.

Contraindications

• CONTRAINDICATIONS Metformin hydrochloride extended-release tablets
• USP are contraindicated in patients with: 1. Severe Renal Impairment (eGFR below 30mL/min/1.73m2) (see WARNINGS and PRECAUTIONS ). 2.Known hypersensitivity to metformin hydrochloride
• USP. 3.Acute or chronic metabolic acidosis
• including diabetic ketoacidosis
• with or without coma. Diabetic ketoacidosis should be treated with insulin.

FDA Warnings

WARNINGS LACTIC ACIDOSIS: Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension and resistant bradyarrhythmias
Risk factors for metformin associated lactic acidosis include renal impairment, concamitent use of certain drugs (e
Steps to reduce the risk of and manage metformin-associated lactic acidosis in these high risk groups are provided (see DOSAGE AND ADMINISTRATION , CONTRAINDICATIONS , AND PRECAUTIONS )

Known Side Effects

10 documented side effects by frequency

Nausea

>10%

Diarrhea

1-10%

Drug Not Working

1-10%

Fatigue

1-10%

Vomiting

1-10%

Weight Loss

1-10%

Shortness of Breath

1-10%

Dizziness

1-10%

Headache

1-10%

Weakness

0.1-1%

Community Discussions

No community discussions found for METFORMIN ER 500 MG yet.

Primary sources

Every figure on this page links back to its primary source. See data sources for full provenance.

DailyMed FDA label search → METFORMIN ER 500 MG openFDA label JSON → METFORMIN ER 500 MG FAERS adverse-event reports → METFORMIN ER 500 MG ClinicalTrials.gov → completed Phase 2+ trials of METFORMIN ER 500 MG

Compare With

9 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral