METFORMIN HCL

Biguanide

Brand names: Metformin HCl

Pregnancy: Category BOral

Mechanism of Action

Other agent

Indications

INDICATIONS & USAGE Metformin Hydrochloride Tablets USP are indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 2 diabetes mellitus.

Contraindications

• CONTRAINDICATIONS Metformin Hydrochloride Tablets USP are contraindicated in patients with: 1. Renal disease or renal dysfunction (e.g.
• as suggested by serum creatinine levels ≥1.5 mg/dL [males]
• ≥1.4 mg/dL [females] or abnormal creatinine clearance) which may also result from conditions such as cardiovascular collapse (shock)
• acute myocardial infarction
• and septicemia (see WARNINGS and PRECAUTIONS ). 2. Known hypersensitivity to metformin hydrochloride 3. Acute or chronic metabolic acidosis

FDA Warnings

WARNINGS Lactic Acidosis: Lactic acidosis is a rare, but serious, metabolic complication that can occur due to metformin accumulation during treatment with Metformin Hydrochloride Tablets USP; when it occurs, it is fatal in approximately 50% of cases
015 fatal cases/1000 patient-years)
Patients with congestive heart failure requiring pharmacologic management, in particular those with unstable or acute congestive heart failure who are at risk of hypoperfusion and hypoxemia, are at increased risk of lactic acidosis
The risk of lactic acidosis increases with the degree of renal dysfunction and the patient’s age

Known Side Effects

10 documented side effects by frequency

Nausea

>10%

Diarrhea

1-10%

Drug Not Working

1-10%

Fatigue

1-10%

Vomiting

1-10%

Weight Loss

1-10%

Shortness of Breath

1-10%

Dizziness

1-10%

Headache

1-10%

Weakness

0.1-1%

Community Discussions

1 Reddit threads analysed for METFORMIN HCL

Overall Sentiment

Slightly positive

Comparison Threads

Avg Post Score

1 upvotes

Patient Experiences (r/pharmacy, r/AskDocs & more)

Chemistry project

I have a chemistry project about the drug metformin hcl and I couldn’t find anything reliable about routes of administration any help would be great

r/pharmacy157y ago

Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.

Compare With

9 available comparisons

Formulations

Dosage Forms

Tablet

Route

Oral