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12.1 Mechanism of Action CONTRAVE has two components: naltrexone, an opioid antagonist, and bupropion, a relatively weak inhibitor of the neuronal reuptake of dopamine and norepinephrine. Nonclinical studies suggest that naltrexone and bupropion have effects on two separate areas of the brain involved in the regulation of food intake: the hypothalamus (appetite regulatory center) and the mesolimbic dopamine circuit (reward system). The exact neurochemical effects of CONTRAVE leading to weight loss are not fully understood.
Contraindications
10 documented side effects by frequency
2 Reddit threads analysed for NALTREXONE HYDROCHLORIDE AND BUPROPION HYDROCHLORIDE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
9 upvotes
Most discussed side effects in community
Have you seen Contrave separated into separate scripts for naltrexone and bupropion before? I've seen other combo drugs split before, but not Contrave. I had a patient where Contrave was too expensive and the prescriber wanted to split it so it would be covered/be cheaper. Naltrexone is only avai
Is it true that you are considering utilizing an over-the-counter weight loss pill to thin down? Or on the other hand maybe you caught wind of a FDA-affirmed diet pill that requires a solution. Endeavouring to locate a safe medicine to enable you to thin down can be testing. Utilize this manual f
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3 available comparisons
Dosage Forms
Tablet
Route
Oral