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Brand names: naratriptan
12.1 Mechanism of Action Naratriptan binds with high affinity to human cloned 5-HT 1B/1D receptors. Migraines are likely due to local cranial vasodilatation and/or to the release of sensory neuropeptides (including substance P and calcitonin gene-related peptide) through nerve endings in the trigeminal system. The therapeutic activity of naratriptan for the treatment of migraine headache is thought to be due to the agonist effects at the 5-HT 1B/1D receptors on intracranial blood vessels (including the arterio-venous anastomoses) and sensory nerves of the trigeminal system, which result in cranial vessel constriction and inhibition of pro-inflammatory neuropeptide release.
Contraindications
11 documented side effects by frequency
7 Reddit threads analysed for NARATRIPTAN
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
61 upvotes
Most discussed side effects in community
This is my first post here, in fact my first post on reddit ever in many years of using it. I've decided to make this post as I have recently gotten back a good chunk of qualitly of life and felt its worth sharing, on the offchance it helps someone else to the same degree. **The Backstory:** I've re
Hi all, I just got out of my 4th or 5th appointment with my neurologist and she told me she's stumped and doesn't know what to do with me anymore. I'm so sad. I'm so angry. I'm only 20, trying to start my life. She said she'd talk to some of her colleagues and call me on tuesday but she looked hopel
I tend to experience more migraines during periods of high stress. I was talking about it with my therapist and we identified a pattern where I get immobilized by stress, then get a migraine because of a break in my routine. Then I really can’t do anything but lay in bed for days and wait until the
Tl;dr - I'm not good at tldr's but basically I tell a long story just to say I really appreciate the staff at the three letter pharmacy I go to lol I've had a migraine going on a week now, and I finally caved and called my doc because of new symptoms and the fact that my sumatriptan wasn't really al
My migraines started around 2000. They're usually mostly on one side (usually the left), and hurt like hell. They would sometimes get so bad that I would have nausea and, rarely, vomiting. They come with sensitivity to light, but no aura. Most of the time they start in the early morning. I wake up
Im so thankful for the wisdom and compassion here. I need the thoughts of you beautiful people!! Please share any ideas you have whether your own experience, medication ideas, what to tell my neuro, etc. I’ve had migraines since I was 12 but only diagnosed last year at age 24 with chronic migraine
So, over the past year or so, I have occasionally had edibles in the weekend (when others drank). Alcohol upsets my stomach and I almost always get a migraine (often already while still drinking my first glass!) Now I have noticed that those edibles (usually 5mg THC, sometimes with CBD, sometimes wi
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
16 available comparisons
Dosage Forms
Tablet
Route
Oral