OMIDENEPAG ISOPROPYL

Other

Brand names: Omlonti

Ophthalmic

Mechanism of Action

12.1 Mechanism of Action Omidenepag is a relatively selective EP2 receptor agonist which decreases intraocular pressure (IOP). The exact mechanism of action is unknown at this time. Elevated IOP represents a major risk factor for glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss.

Indications

1 INDICATIONS AND USAGE Omlonti (omidenepag isopropyl ophthalmic solution) 0.002%

is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Omlonti (omidenepag isopropyl ophthalmic solution) 0.002%

is a relatively selective prostaglandin E2 (EP2) receptor agonist

indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. ( 1 )

Contraindications

• 4 CONTRAINDICATIONS None. None ( 4 )

FDA Warnings

5 WARNINGS AND PRECAUTIONS Pigmentation ( 5
Omlonti should be used with caution in aphakic patients, in pseudophakic patients, or in patients with known risk factors for macular edema
5 Risk of Contamination and Potential Injury to the Eye Advise patients to avoid touching the tip of the bottle to the eye or any surface, as this may contaminate the solution

Known Side Effects

2 documented side effects by frequency

Blurred Vision

1-10%

Cough

0.1-1%

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Formulations

Dosage Forms

Tablet

Route

Ophthalmic