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Brand names: Pantoprazole, Protonix
12.1 Mechanism of Action Pantoprazole is a PPI that suppresses the final step in gastric acid production by covalently binding to the (H + , K + )-ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect leads to inhibition of both basal and stimulated gastric acid secretion, irrespective of the stimulus. The binding to the (H + , K + )-ATPase results in a duration of antisecretory effect that persists longer than 24 hours for all doses tested (20 mg to 120 mg).
Contraindications
10 documented side effects by frequency
15 Reddit threads analysed for PANTOPRAZOLE
Overall Sentiment
Mixed
Comparison Threads
0
Avg Post Score
102 upvotes
Most discussed side effects in community
Update: I’ve been eating some of my trigger foods (caffeine, chocolate, and garlic) just to see what would happen. I normally couldn’t even have these with my 2x/day pantoprazole without being curled up in a ball, but aside from some VERY mild pain under my ribs, I feel amazing! Update #2: I’ve been
Hi i am 25f. Heres my story. When I was 19, my weight was 54, the heaviest ive been in my life. As years go by i started to lose weight more and more up until this year I was 41 kg. I keep losing weight throughout the years because i simply couldnt eat. I also had lots of abdominal pain episodes th
Suffered from bouts of GERD ever since I was a teenager. I had to take pantoprazole 40mg for about three years and was on the waiting list for a sphincter surgery. By chance I started to drink mallow tea (it has to be this mallow: https://en.wikipedia.org/wiki/Malva\_sylvestris) and my reflux has si
Guys, I've been suffering from constant belching since early 2018, then after I went out drinking with friends on the 24th of december 2019 I woke up with a pretty bad throat pain (LPR). I thought I caught a cold but the pain never went away... 6 months after as if the constant throat pain wasn't en
I so wish that it was more widely known that GERD really can be a chronic condition. So many sufferers just have to live with their symptoms day in and day out, with little to no relief. I go through stages of being okay as long as I take my 40mg pantoprazole daily, and then one small trigger (or st
Last year was really tough for me as I was hospitalized twice because of GERD. I couldn't sleep because of the pain and flare-ups, I cried almost everyday and felt very desperate. I was prescribed Pantoprazole and Carafate, took both for 8 months. I lost weight very fast because I could barely eat,
Fuck this disease. I've been panicking for a while thinking I'm gonna die from a heart atrack, I swear it felt so reall! Told my doc about it, and he switched Omeprazole with Pantoprazole and it went away. Made this post just in case someone gets the same symptoms and can't tell why.
Good morning, I wanted to take the time to kinda go through my struggle with GERD, Gastritis, and other gastro esophageal issues and how I've paved the path to improvement and the ceasing of my symptoms It all started at the end of October 2023. I was 27 yeara old. I had, for many years, maintained
Community discussions are sourced from public Reddit threads. Content reflects individual opinions and is not medical advice.
6 available comparisons
Dosage Forms
Tablet
Route
Oral