PHENYLEPHRINE HYDROCHLORIDE

Electrolyte / Mineral

Brand names: Phenylephrine hydrochloride

Intravenous

Mechanism of Action

12.1 Mechanism of Action Phenylephrine hydrochloride is an α-1 adrenergic receptor agonist.

Indications

1 INDICATIONS & USAGE Phenylephrine hydrochloride Injection

Contraindications

• 4 CONTRAINDICATIONS None None

FDA Warnings

5 WARNINGS AND PRECAUTIONS Exacerbation of Angina, Heart Failure, or Pulmonary Arterial Hypertension: Phenylephrine hydrochloride injection can precipitate angina in patients with severe arteriosclerosis or history of angina, exacerbate underlying heart failure, and increase pulmonary arterial pressure
7 Risk of Augmented Pressor Affect in Patients with Autonomic Dysfunction The increasing blood pressure response to adrenergic drugs, including Phenylephrine hydrochloride injection, can be increased in patients with autonomic dysfunction, as may occur with spinal cord injuries

Known Side Effects

13 documented side effects by frequency

Drug Not Working

>10%

Fatigue

1-10%

Headache

1-10%

Nausea

1-10%

Diarrhea

1-10%

Shortness of Breath

1-10%

Joint Pain

1-10%

Dizziness

0.1-1%

Vomiting

0.1-1%

Rash

0.1-1%

Weakness

0.1-1%

Fever

0.1-1%

Limb Pain

0.1-1%

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Formulations

Dosage Forms

Tablet

Route

Intravenous