SUCCIMER

Other

Brand names: Chemet

Oral

12.1 Mechanism of Action Succimer is a lead chelator; it forms water soluble chelates and, consequently, increases the urinary excretion of lead.

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Contraindications

• 4 CONTRAINDICATIONS CHEMET is contraindicated in patients with a history of hypersensitivity reaction to succimer. Reactions have included mucocutaneous vesicular eruptions
• urticaria
• and angioedema [see Warnings and Precautions (5.1) ] . Patients with a history of hypersensitivity reaction to succimer. ( 4 )

5 WARNINGS AND PRECAUTIONS Hypersensitivity and dermatologic reactions: Interrupt treatment if rash or mucocutaneous vesicular eruptions occur
Only rechallenge patients who developed neutropenia with CHEMET therapy if the benefit clearly outweighs the potential risk

7 documented side effects by frequency

Joint Pain

1-10%

High Blood Pressure

1-10%

Weight Gain

1-10%

Condition Worsened

0.1-1%

Dizziness

0.1-1%

Weakness

0.1-1%

Back Pain

0.1-1%

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Dosage Forms

Tablet

Route

Oral